DERIVADO DE CICLOALQUILUREA
SE REFIERE A COMPUESTOS DERIVADOS DE CICLOALQUILUREA DE FORMULA (1) DONDE R1, R2, R3, R4, A1, A2, A3, L1, L2, n Y EL ANILLO G SON TAL COMO SE DESCRIBEN EN EL PRESENTE DOCUMENTO. SON COMPUESTOS PREFERIDOS: 4-(5-CICLOPROPIL-1,2-OXAZOL-3-IL)-N-{(1S,6R)-2,2-DIFLUORO-6-[4-(PROPAN-2-IL)PIPERAZIN-1-IL]CICL...
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| creator | FUNAKOSHI, Yuta KOMIYA, Masafumi IDEUE, Eiji LEE, Shoukou UESUGI, Shunichiro |
| description | SE REFIERE A COMPUESTOS DERIVADOS DE CICLOALQUILUREA DE FORMULA (1) DONDE R1, R2, R3, R4, A1, A2, A3, L1, L2, n Y EL ANILLO G SON TAL COMO SE DESCRIBEN EN EL PRESENTE DOCUMENTO. SON COMPUESTOS PREFERIDOS: 4-(5-CICLOPROPIL-1,2-OXAZOL-3-IL)-N-{(1S,6R)-2,2-DIFLUORO-6-[4-(PROPAN-2-IL)PIPERAZIN-1-IL]CICLOHEXIL}-4-METILPIPERIDINA-1-CARBOXAMIDA; 4-(5-CICLOPROPIL-1,2,4-OXADIAZOL-3-IL)-N-{(1S,6R)-2,2-DIFLUORO-6-[4-(PROPAN-2-IL)PIPERAZIN-1-IL]CICLOHEXIL}-4-METILPIPERIDINA-1-CARBOXAMIDA; N-{(1R,6S)-2,2-DIFLUORO-6-[3-(PROPAN-2-IL)-3,8-DIAZABICICLO[3.2.1]OCTAN-8-IL]CICLOHEXIL}-4-METIL-4-(4-METILFENIL)PIPERIDINA-1-CARBOXAMIDA; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS TIENEN ACTIVIDAD AGONISTA PARA EL RECEPTOR DE OREXINA TIPO 2 SIENDO UTILES EN EL TRATAMIENTO DE NARCOLEPSIA, HIPERSOMNIA IDIOPATICA, HIPERSOMNIA, SINDROME DE APNEA DEL SUENO.
The present invention relates to a medicament for treating or preventing a disease related to orexin receptor, especially orexin type 2 receptor, comprising a new compound having a urea structure or a pharmaceutically acceptable salt thereof as an active ingredient. In more detail, the present invention relates to a medicament for treating or preventing narcolepsy, idiopathic hypersomnia, hypersomnia, sleep apnea syndrome, etc. |
| format | Patent |
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The present invention relates to a medicament for treating or preventing a disease related to orexin receptor, especially orexin type 2 receptor, comprising a new compound having a urea structure or a pharmaceutically acceptable salt thereof as an active ingredient. In more detail, the present invention relates to a medicament for treating or preventing narcolepsy, idiopathic hypersomnia, hypersomnia, sleep apnea syndrome, etc.</description><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221107&DB=EPODOC&CC=PE&NR=20221730A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221107&DB=EPODOC&CC=PE&NR=20221730A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FUNAKOSHI, Yuta</creatorcontrib><creatorcontrib>KOMIYA, Masafumi</creatorcontrib><creatorcontrib>IDEUE, Eiji</creatorcontrib><creatorcontrib>LEE, Shoukou</creatorcontrib><creatorcontrib>UESUGI, Shunichiro</creatorcontrib><title>DERIVADO DE CICLOALQUILUREA</title><description>SE REFIERE A COMPUESTOS DERIVADOS DE CICLOALQUILUREA DE FORMULA (1) DONDE R1, R2, R3, R4, A1, A2, A3, L1, L2, n Y EL ANILLO G SON TAL COMO SE DESCRIBEN EN EL PRESENTE DOCUMENTO. SON COMPUESTOS PREFERIDOS: 4-(5-CICLOPROPIL-1,2-OXAZOL-3-IL)-N-{(1S,6R)-2,2-DIFLUORO-6-[4-(PROPAN-2-IL)PIPERAZIN-1-IL]CICLOHEXIL}-4-METILPIPERIDINA-1-CARBOXAMIDA; 4-(5-CICLOPROPIL-1,2,4-OXADIAZOL-3-IL)-N-{(1S,6R)-2,2-DIFLUORO-6-[4-(PROPAN-2-IL)PIPERAZIN-1-IL]CICLOHEXIL}-4-METILPIPERIDINA-1-CARBOXAMIDA; N-{(1R,6S)-2,2-DIFLUORO-6-[3-(PROPAN-2-IL)-3,8-DIAZABICICLO[3.2.1]OCTAN-8-IL]CICLOHEXIL}-4-METIL-4-(4-METILFENIL)PIPERIDINA-1-CARBOXAMIDA; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS TIENEN ACTIVIDAD AGONISTA PARA EL RECEPTOR DE OREXINA TIPO 2 SIENDO UTILES EN EL TRATAMIENTO DE NARCOLEPSIA, HIPERSOMNIA IDIOPATICA, HIPERSOMNIA, SINDROME DE APNEA DEL SUENO.
The present invention relates to a medicament for treating or preventing a disease related to orexin receptor, especially orexin type 2 receptor, comprising a new compound having a urea structure or a pharmaceutically acceptable salt thereof as an active ingredient. In more detail, the present invention relates to a medicament for treating or preventing narcolepsy, idiopathic hypersomnia, hypersomnia, sleep apnea syndrome, etc.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJB2cQ3yDHN08VdwcVVw9nT28Xf0CQz19AkNcnXkYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxAa5GBkZGhubGBo6GxsSoAQBJoyBk</recordid><startdate>20221107</startdate><enddate>20221107</enddate><creator>FUNAKOSHI, Yuta</creator><creator>KOMIYA, Masafumi</creator><creator>IDEUE, Eiji</creator><creator>LEE, Shoukou</creator><creator>UESUGI, Shunichiro</creator><scope>EVB</scope></search><sort><creationdate>20221107</creationdate><title>DERIVADO DE CICLOALQUILUREA</title><author>FUNAKOSHI, Yuta ; KOMIYA, Masafumi ; IDEUE, Eiji ; LEE, Shoukou ; UESUGI, Shunichiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PE20221730A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>FUNAKOSHI, Yuta</creatorcontrib><creatorcontrib>KOMIYA, Masafumi</creatorcontrib><creatorcontrib>IDEUE, Eiji</creatorcontrib><creatorcontrib>LEE, Shoukou</creatorcontrib><creatorcontrib>UESUGI, Shunichiro</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FUNAKOSHI, Yuta</au><au>KOMIYA, Masafumi</au><au>IDEUE, Eiji</au><au>LEE, Shoukou</au><au>UESUGI, Shunichiro</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVADO DE CICLOALQUILUREA</title><date>2022-11-07</date><risdate>2022</risdate><abstract>SE REFIERE A COMPUESTOS DERIVADOS DE CICLOALQUILUREA DE FORMULA (1) DONDE R1, R2, R3, R4, A1, A2, A3, L1, L2, n Y EL ANILLO G SON TAL COMO SE DESCRIBEN EN EL PRESENTE DOCUMENTO. SON COMPUESTOS PREFERIDOS: 4-(5-CICLOPROPIL-1,2-OXAZOL-3-IL)-N-{(1S,6R)-2,2-DIFLUORO-6-[4-(PROPAN-2-IL)PIPERAZIN-1-IL]CICLOHEXIL}-4-METILPIPERIDINA-1-CARBOXAMIDA; 4-(5-CICLOPROPIL-1,2,4-OXADIAZOL-3-IL)-N-{(1S,6R)-2,2-DIFLUORO-6-[4-(PROPAN-2-IL)PIPERAZIN-1-IL]CICLOHEXIL}-4-METILPIPERIDINA-1-CARBOXAMIDA; N-{(1R,6S)-2,2-DIFLUORO-6-[3-(PROPAN-2-IL)-3,8-DIAZABICICLO[3.2.1]OCTAN-8-IL]CICLOHEXIL}-4-METIL-4-(4-METILFENIL)PIPERIDINA-1-CARBOXAMIDA; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS TIENEN ACTIVIDAD AGONISTA PARA EL RECEPTOR DE OREXINA TIPO 2 SIENDO UTILES EN EL TRATAMIENTO DE NARCOLEPSIA, HIPERSOMNIA IDIOPATICA, HIPERSOMNIA, SINDROME DE APNEA DEL SUENO.
The present invention relates to a medicament for treating or preventing a disease related to orexin receptor, especially orexin type 2 receptor, comprising a new compound having a urea structure or a pharmaceutically acceptable salt thereof as an active ingredient. In more detail, the present invention relates to a medicament for treating or preventing narcolepsy, idiopathic hypersomnia, hypersomnia, sleep apnea syndrome, etc.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DERIVADO DE CICLOALQUILUREA |
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