INHIBIDORES DE TRIAZOL GLICOLATO OXIDASA
SE REFIERE A COMPUESTOS TRIAZOL DE ACIDOS CARBOXILICOS DE FORMULA (I) DONDE A2, A3, A4, A5, A6, Z1, Z2 Y L SON COMO SE DEFINEN EN LA DESCRIPCION. SON COMPUESTOS PREFERIDOS: ACIDO 5-(4-(4-ACETILPIPERAZIN-1-IL)FENOXI)-1H-1,2,3-TRIAZOL-4-CARBOXILICO; ACIDO 5-(4-(1H-PIRAZOL-1-IL)FENOXI)-1H-1,2,3-TRIAZOL...
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| creator | THAKUR, Pallavi ZAMBONI, Robert FERNANDES, Miguel Xavier MAAG, Hans AKBARIROMANI, Elham LEBLANC, Yves BEAULIEU, Marc-Andre |
| description | SE REFIERE A COMPUESTOS TRIAZOL DE ACIDOS CARBOXILICOS DE FORMULA (I) DONDE A2, A3, A4, A5, A6, Z1, Z2 Y L SON COMO SE DEFINEN EN LA DESCRIPCION. SON COMPUESTOS PREFERIDOS: ACIDO 5-(4-(4-ACETILPIPERAZIN-1-IL)FENOXI)-1H-1,2,3-TRIAZOL-4-CARBOXILICO; ACIDO 5-(4-(1H-PIRAZOL-1-IL)FENOXI)-1H-1,2,3-TRIAZOL-4-CARBOXILICO; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE GLICOLATO OXIDASA SIENDO UTILES EN EL TRATAMIENTO DE HIPEROXALURIA PRIMARIA TIPO I (PH1).
The present invention provides triazole carboxylic acids and related compounds, as well as pharmaceutically acceptable salts thereof, which are useful as glycolate oxidase inhibitors. Pharmaceutical compositions and methods for treating primary hyperoxaluria, type I (PH) and kidney stones are also described. |
| format | Patent |
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The present invention provides triazole carboxylic acids and related compounds, as well as pharmaceutically acceptable salts thereof, which are useful as glycolate oxidase inhibitors. Pharmaceutical compositions and methods for treating primary hyperoxaluria, type I (PH) and kidney stones are also described.</description><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210518&DB=EPODOC&CC=PE&NR=20210859A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210518&DB=EPODOC&CC=PE&NR=20210859A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>THAKUR, Pallavi</creatorcontrib><creatorcontrib>ZAMBONI, Robert</creatorcontrib><creatorcontrib>FERNANDES, Miguel Xavier</creatorcontrib><creatorcontrib>MAAG, Hans</creatorcontrib><creatorcontrib>AKBARIROMANI, Elham</creatorcontrib><creatorcontrib>LEBLANC, Yves</creatorcontrib><creatorcontrib>BEAULIEU, Marc-Andre</creatorcontrib><title>INHIBIDORES DE TRIAZOL GLICOLATO OXIDASA</title><description>SE REFIERE A COMPUESTOS TRIAZOL DE ACIDOS CARBOXILICOS DE FORMULA (I) DONDE A2, A3, A4, A5, A6, Z1, Z2 Y L SON COMO SE DEFINEN EN LA DESCRIPCION. SON COMPUESTOS PREFERIDOS: ACIDO 5-(4-(4-ACETILPIPERAZIN-1-IL)FENOXI)-1H-1,2,3-TRIAZOL-4-CARBOXILICO; ACIDO 5-(4-(1H-PIRAZOL-1-IL)FENOXI)-1H-1,2,3-TRIAZOL-4-CARBOXILICO; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE GLICOLATO OXIDASA SIENDO UTILES EN EL TRATAMIENTO DE HIPEROXALURIA PRIMARIA TIPO I (PH1).
The present invention provides triazole carboxylic acids and related compounds, as well as pharmaceutically acceptable salts thereof, which are useful as glycolate oxidase inhibitors. Pharmaceutical compositions and methods for treating primary hyperoxaluria, type I (PH) and kidney stones are also described.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDw9PPwdPJ08Q9yDVZwcVUICfJ0jPL3UXD38XT293EM8Vfwj_B0cQx25GFgTUvMKU7lhdLcDIpuriHOHrqpBfnxqcUFicmpeakl8QGuRgZGhgYWppaOhsbEqAEACDIkFA</recordid><startdate>20210518</startdate><enddate>20210518</enddate><creator>THAKUR, Pallavi</creator><creator>ZAMBONI, Robert</creator><creator>FERNANDES, Miguel Xavier</creator><creator>MAAG, Hans</creator><creator>AKBARIROMANI, Elham</creator><creator>LEBLANC, Yves</creator><creator>BEAULIEU, Marc-Andre</creator><scope>EVB</scope></search><sort><creationdate>20210518</creationdate><title>INHIBIDORES DE TRIAZOL GLICOLATO OXIDASA</title><author>THAKUR, Pallavi ; ZAMBONI, Robert ; FERNANDES, Miguel Xavier ; MAAG, Hans ; AKBARIROMANI, Elham ; LEBLANC, Yves ; BEAULIEU, Marc-Andre</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PE20210859A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>THAKUR, Pallavi</creatorcontrib><creatorcontrib>ZAMBONI, Robert</creatorcontrib><creatorcontrib>FERNANDES, Miguel Xavier</creatorcontrib><creatorcontrib>MAAG, Hans</creatorcontrib><creatorcontrib>AKBARIROMANI, Elham</creatorcontrib><creatorcontrib>LEBLANC, Yves</creatorcontrib><creatorcontrib>BEAULIEU, Marc-Andre</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>THAKUR, Pallavi</au><au>ZAMBONI, Robert</au><au>FERNANDES, Miguel Xavier</au><au>MAAG, Hans</au><au>AKBARIROMANI, Elham</au><au>LEBLANC, Yves</au><au>BEAULIEU, Marc-Andre</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INHIBIDORES DE TRIAZOL GLICOLATO OXIDASA</title><date>2021-05-18</date><risdate>2021</risdate><abstract>SE REFIERE A COMPUESTOS TRIAZOL DE ACIDOS CARBOXILICOS DE FORMULA (I) DONDE A2, A3, A4, A5, A6, Z1, Z2 Y L SON COMO SE DEFINEN EN LA DESCRIPCION. SON COMPUESTOS PREFERIDOS: ACIDO 5-(4-(4-ACETILPIPERAZIN-1-IL)FENOXI)-1H-1,2,3-TRIAZOL-4-CARBOXILICO; ACIDO 5-(4-(1H-PIRAZOL-1-IL)FENOXI)-1H-1,2,3-TRIAZOL-4-CARBOXILICO; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE GLICOLATO OXIDASA SIENDO UTILES EN EL TRATAMIENTO DE HIPEROXALURIA PRIMARIA TIPO I (PH1).
The present invention provides triazole carboxylic acids and related compounds, as well as pharmaceutically acceptable salts thereof, which are useful as glycolate oxidase inhibitors. Pharmaceutical compositions and methods for treating primary hyperoxaluria, type I (PH) and kidney stones are also described.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | INHIBIDORES DE TRIAZOL GLICOLATO OXIDASA |
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