ERITROPOYETINA HUMANA MODIFICADA
Una eritropoyetina humana modificada con un tiempo de vida media en plasma aumentado, con actividad eritropoyetica menor al 0,5 % en relacion a una eritropoyetina nativa, que mantiene su capacidad neuroprotectora y neuroplastica, que comprende la mutacion de al menos uno de los sitios de union al re...
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creator | KRATJE, Ricardo APARICIO, Gabriela I ETCHEVERRIGARAY, Marina SCORTICATI, Camila BURGI-FISSOLO, Maria de los Milagros DORELLA, Aquiles OGGERO-EBERHARDT, Marcos |
description | Una eritropoyetina humana modificada con un tiempo de vida media en plasma aumentado, con actividad eritropoyetica menor al 0,5 % en relacion a una eritropoyetina nativa, que mantiene su capacidad neuroprotectora y neuroplastica, que comprende la mutacion de al menos uno de los sitios de union al receptor homodimerico o heterodimerico mediante la incorporacion de sitios consenso de N-glicosilacion
A modified human erythropoietin with an increased plasma half-life, with an erythropoietic activity of less than 0.5% in relation to a native erythropoietin, which maintains the neuroprotective and neuroplastic capacity, which comprises the mutation of at least one of the binding sites the homodimeric or heterodimeric receptor by incorporating consensus sites for N-glycosylation. |
format | Patent |
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A modified human erythropoietin with an increased plasma half-life, with an erythropoietic activity of less than 0.5% in relation to a native erythropoietin, which maintains the neuroprotective and neuroplastic capacity, which comprises the mutation of at least one of the binding sites the homodimeric or heterodimeric receptor by incorporating consensus sites for N-glycosylation.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBwDfIMCfIP8I90DfH0c1TwCPV1BFK-_i6ebp7Oji6OPAysaYk5xam8UJqbQdHNNcTZQze1ID8-tbggMTk1L7UkPsDVyMDI0MDCyNzR0JgYNQAE9yH2</recordid><startdate>20210430</startdate><enddate>20210430</enddate><creator>KRATJE, Ricardo</creator><creator>APARICIO, Gabriela I</creator><creator>ETCHEVERRIGARAY, Marina</creator><creator>SCORTICATI, Camila</creator><creator>BURGI-FISSOLO, Maria de los Milagros</creator><creator>DORELLA, Aquiles</creator><creator>OGGERO-EBERHARDT, Marcos</creator><scope>EVB</scope></search><sort><creationdate>20210430</creationdate><title>ERITROPOYETINA HUMANA MODIFICADA</title><author>KRATJE, Ricardo ; APARICIO, Gabriela I ; ETCHEVERRIGARAY, Marina ; SCORTICATI, Camila ; BURGI-FISSOLO, Maria de los Milagros ; DORELLA, Aquiles ; OGGERO-EBERHARDT, Marcos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PE20210827A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2021</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KRATJE, Ricardo</creatorcontrib><creatorcontrib>APARICIO, Gabriela I</creatorcontrib><creatorcontrib>ETCHEVERRIGARAY, Marina</creatorcontrib><creatorcontrib>SCORTICATI, Camila</creatorcontrib><creatorcontrib>BURGI-FISSOLO, Maria de los Milagros</creatorcontrib><creatorcontrib>DORELLA, Aquiles</creatorcontrib><creatorcontrib>OGGERO-EBERHARDT, Marcos</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KRATJE, Ricardo</au><au>APARICIO, Gabriela I</au><au>ETCHEVERRIGARAY, Marina</au><au>SCORTICATI, Camila</au><au>BURGI-FISSOLO, Maria de los Milagros</au><au>DORELLA, Aquiles</au><au>OGGERO-EBERHARDT, Marcos</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ERITROPOYETINA HUMANA MODIFICADA</title><date>2021-04-30</date><risdate>2021</risdate><abstract>Una eritropoyetina humana modificada con un tiempo de vida media en plasma aumentado, con actividad eritropoyetica menor al 0,5 % en relacion a una eritropoyetina nativa, que mantiene su capacidad neuroprotectora y neuroplastica, que comprende la mutacion de al menos uno de los sitios de union al receptor homodimerico o heterodimerico mediante la incorporacion de sitios consenso de N-glicosilacion
A modified human erythropoietin with an increased plasma half-life, with an erythropoietic activity of less than 0.5% in relation to a native erythropoietin, which maintains the neuroprotective and neuroplastic capacity, which comprises the mutation of at least one of the binding sites the homodimeric or heterodimeric receptor by incorporating consensus sites for N-glycosylation.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | ERITROPOYETINA HUMANA MODIFICADA |
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