COMPUESTOS DE PIRROLO[2,3-D]PIRIMIDINA
SE REFIERE A COMPUESTOS DERIVADOS DE PIRROLO[2,3-d]PIRIMIDINA DE FORMULA (I) DONDE A ES UN ANILLO HETEROCICLILO TALES COMO PIPERIDINILO, PIRROLIDINILO, AZETIDINILO O PIPERAZINILO OPCIONALMENTE SUSTITUIDOS CON HALO, CARBOXI, CN, OXO, ALQUILO(C1-C8), ENTRE OTROS. SON COMPUESTOS PREFERIDOS: N-(TRANS-4-...
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| creator | HARTMANN, SUSAN J HUANG, HORNGIH ACKER, BRAD ALAN PROMO, MICHELE ANN XIE, JIN JACOBSEN, ERIC JON WOLFSON, SERGEY GREGORY |
| description | SE REFIERE A COMPUESTOS DERIVADOS DE PIRROLO[2,3-d]PIRIMIDINA DE FORMULA (I) DONDE A ES UN ANILLO HETEROCICLILO TALES COMO PIPERIDINILO, PIRROLIDINILO, AZETIDINILO O PIPERAZINILO OPCIONALMENTE SUSTITUIDOS CON HALO, CARBOXI, CN, OXO, ALQUILO(C1-C8), ENTRE OTROS. SON COMPUESTOS PREFERIDOS: N-(TRANS-4-{[(3-METOXIPIPERIDIN-1-IL)SULFONIL]METIL}CICLOHEXIL)-N-METIL-7H-PIRROLO[2,3-d]PIRIMIDIN-4-AMINA; (3R)-1-[({(1S,3R,4S)-3-METIL-4-[METIL(7H-PIRROLO[2,3-d]PIRIMIDIN-4-IL)AMINO]-CICLOHEXIL}METIL)SULFONIL]PIPERIDIN-3-OL; {1-[({TRANS-4-[METIL(7H-PIRROLO[2,3-d]PIRIMIDIN-4-IL)AMINO]CICLOHEXIL}METIL)-SULFONIL]PIPERIDIN-3-IL}METANOL; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE QUINASAS DE JANUS (JAK) SIENDO UTILES EN EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER, ARTRITIS, DIABETES, LEUCEMIA, LUPUS
Described herein are pyrrolo[2,3-d]pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing these compounds, and methods for their preparation. |
| format | Patent |
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Described herein are pyrrolo[2,3-d]pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing these compounds, and methods for their preparation.</description><language>spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120810&DB=EPODOC&CC=PE&NR=20121077A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120810&DB=EPODOC&CC=PE&NR=20121077A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HARTMANN, SUSAN J</creatorcontrib><creatorcontrib>HUANG, HORNGIH</creatorcontrib><creatorcontrib>ACKER, BRAD ALAN</creatorcontrib><creatorcontrib>PROMO, MICHELE ANN</creatorcontrib><creatorcontrib>XIE, JIN</creatorcontrib><creatorcontrib>JACOBSEN, ERIC JON</creatorcontrib><creatorcontrib>WOLFSON, SERGEY GREGORY</creatorcontrib><title>COMPUESTOS DE PIRROLO[2,3-D]PIRIMIDINA</title><description>SE REFIERE A COMPUESTOS DERIVADOS DE PIRROLO[2,3-d]PIRIMIDINA DE FORMULA (I) DONDE A ES UN ANILLO HETEROCICLILO TALES COMO PIPERIDINILO, PIRROLIDINILO, AZETIDINILO O PIPERAZINILO OPCIONALMENTE SUSTITUIDOS CON HALO, CARBOXI, CN, OXO, ALQUILO(C1-C8), ENTRE OTROS. SON COMPUESTOS PREFERIDOS: N-(TRANS-4-{[(3-METOXIPIPERIDIN-1-IL)SULFONIL]METIL}CICLOHEXIL)-N-METIL-7H-PIRROLO[2,3-d]PIRIMIDIN-4-AMINA; (3R)-1-[({(1S,3R,4S)-3-METIL-4-[METIL(7H-PIRROLO[2,3-d]PIRIMIDIN-4-IL)AMINO]-CICLOHEXIL}METIL)SULFONIL]PIPERIDIN-3-OL; {1-[({TRANS-4-[METIL(7H-PIRROLO[2,3-d]PIRIMIDIN-4-IL)AMINO]CICLOHEXIL}METIL)-SULFONIL]PIPERIDIN-3-IL}METANOL; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE QUINASAS DE JANUS (JAK) SIENDO UTILES EN EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER, ARTRITIS, DIABETES, LEUCEMIA, LUPUS
Described herein are pyrrolo[2,3-d]pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing these compounds, and methods for their preparation.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBz9vcNCHUNDvEPVnBxVQjwDAry9_GPNtIx1nWJBfI8fT1dPP0ceRhY0xJzilN5oTQ3g6Kba4izh25qQX58anFBYnJqXmpJfICrkYGhkaGBubmjoTExagDSmiOh</recordid><startdate>20120810</startdate><enddate>20120810</enddate><creator>HARTMANN, SUSAN J</creator><creator>HUANG, HORNGIH</creator><creator>ACKER, BRAD ALAN</creator><creator>PROMO, MICHELE ANN</creator><creator>XIE, JIN</creator><creator>JACOBSEN, ERIC JON</creator><creator>WOLFSON, SERGEY GREGORY</creator><scope>EVB</scope></search><sort><creationdate>20120810</creationdate><title>COMPUESTOS DE PIRROLO[2,3-D]PIRIMIDINA</title><author>HARTMANN, SUSAN J ; HUANG, HORNGIH ; ACKER, BRAD ALAN ; PROMO, MICHELE ANN ; XIE, JIN ; JACOBSEN, ERIC JON ; WOLFSON, SERGEY GREGORY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_PE20121077A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>spa</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HARTMANN, SUSAN J</creatorcontrib><creatorcontrib>HUANG, HORNGIH</creatorcontrib><creatorcontrib>ACKER, BRAD ALAN</creatorcontrib><creatorcontrib>PROMO, MICHELE ANN</creatorcontrib><creatorcontrib>XIE, JIN</creatorcontrib><creatorcontrib>JACOBSEN, ERIC JON</creatorcontrib><creatorcontrib>WOLFSON, SERGEY GREGORY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HARTMANN, SUSAN J</au><au>HUANG, HORNGIH</au><au>ACKER, BRAD ALAN</au><au>PROMO, MICHELE ANN</au><au>XIE, JIN</au><au>JACOBSEN, ERIC JON</au><au>WOLFSON, SERGEY GREGORY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPUESTOS DE PIRROLO[2,3-D]PIRIMIDINA</title><date>2012-08-10</date><risdate>2012</risdate><abstract>SE REFIERE A COMPUESTOS DERIVADOS DE PIRROLO[2,3-d]PIRIMIDINA DE FORMULA (I) DONDE A ES UN ANILLO HETEROCICLILO TALES COMO PIPERIDINILO, PIRROLIDINILO, AZETIDINILO O PIPERAZINILO OPCIONALMENTE SUSTITUIDOS CON HALO, CARBOXI, CN, OXO, ALQUILO(C1-C8), ENTRE OTROS. SON COMPUESTOS PREFERIDOS: N-(TRANS-4-{[(3-METOXIPIPERIDIN-1-IL)SULFONIL]METIL}CICLOHEXIL)-N-METIL-7H-PIRROLO[2,3-d]PIRIMIDIN-4-AMINA; (3R)-1-[({(1S,3R,4S)-3-METIL-4-[METIL(7H-PIRROLO[2,3-d]PIRIMIDIN-4-IL)AMINO]-CICLOHEXIL}METIL)SULFONIL]PIPERIDIN-3-OL; {1-[({TRANS-4-[METIL(7H-PIRROLO[2,3-d]PIRIMIDIN-4-IL)AMINO]CICLOHEXIL}METIL)-SULFONIL]PIPERIDIN-3-IL}METANOL; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE QUINASAS DE JANUS (JAK) SIENDO UTILES EN EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER, ARTRITIS, DIABETES, LEUCEMIA, LUPUS
Described herein are pyrrolo[2,3-d]pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing these compounds, and methods for their preparation.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | COMPUESTOS DE PIRROLO[2,3-D]PIRIMIDINA |
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