(2R,3R,4S,5R,2'R,3'R,4'S,5'S)-2,2'-{TRANS-1,4-CICLOHEXANODIILBIS-[IMINO(2-{[2-(1-METIL-1H-IMIDAZOL-4-IL)ETIL]AMINO}-9H-PURIN-6,9-DIIL)]}BIS[5-(2-ETIL-2H-TETRAZOL-5-IL)TETRAHIDRO-3,4-FURANODIOL] COMO AGONISTA A2A

SE REFIERE A SALES Y SOLVATOS DE (2R,3R,4S,5R,2'R,3'R,4'S,5'S)-2,2'-{TRANS-1,4-CICLOHEXANODIILBIS-[IMINO(2-{[2-(1-METIL-1H-IMIDAZOL-4-IL)ETIL]AMINO}-9H-PURIN-6,9-DIIL)]}BIS[5-(2-ETIL-2H-TETRAZOL-5-IL)TETRAHIDRO-3,4-FURANODIOL] Y UN PROCEDIMIENTO DE PREPARACION. SE REFIERE TA...

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Hauptverfasser: BLATCHER PHILIP, COUSINS RICHARD PETER CHARLES, EVANS DEREK NORMAN
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creator BLATCHER PHILIP
COUSINS RICHARD PETER CHARLES
EVANS DEREK NORMAN
description SE REFIERE A SALES Y SOLVATOS DE (2R,3R,4S,5R,2'R,3'R,4'S,5'S)-2,2'-{TRANS-1,4-CICLOHEXANODIILBIS-[IMINO(2-{[2-(1-METIL-1H-IMIDAZOL-4-IL)ETIL]AMINO}-9H-PURIN-6,9-DIIL)]}BIS[5-(2-ETIL-2H-TETRAZOL-5-IL)TETRAHIDRO-3,4-FURANODIOL] Y UN PROCEDIMIENTO DE PREPARACION. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA. DICHO COMPUESTO ES AGONISTA POTENTE DEL RECEPTOR DE ADENOSINA A2A, UTIL EN EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS TALES COMO ASMA Y ENFERMEDAD PULMONAR OBSTRUCTIVA CRONICA A compound of formula (I) and salts and solvates thereof are disclosed. Compounds of formula (I) are agonists of the adenosine A2A receptor and are believed to be of potential use in the treatment of inflammatory diseases such as asthma and chronic obstructive pulmonary disease.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title (2R,3R,4S,5R,2'R,3'R,4'S,5'S)-2,2'-{TRANS-1,4-CICLOHEXANODIILBIS-[IMINO(2-{[2-(1-METIL-1H-IMIDAZOL-4-IL)ETIL]AMINO}-9H-PURIN-6,9-DIIL)]}BIS[5-(2-ETIL-2H-TETRAZOL-5-IL)TETRAHIDRO-3,4-FURANODIOL] COMO AGONISTA A2A
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