Halogenation using halo-vilsmeier reagent

The invention provides an improved process for the preparation of a halogenated steroidal diene. The process involves the simultaneous transformation of the steroidal 3-one to 3-halo and 17-carboxylic acid to 17-carboxamide in a single reaction without the isolation of an intermediate. The process t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	KLEIN DONALD NATHANIEL, OWINGS FRANKLIN FELL, MEWSHAW RICHARD ERIC, BAINE NEIL HOWARD
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
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