Colonic drug delivery formulation
Disclosed is a delayed release drug formulation for delivery of a drug to the colon comprising a particle with a core and a coating for the core, the core comprising a drug and the coating comprising a single layer of a mixture of a first material which is susceptible to attack by colonic bacteria a...
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| creator | Ibekwe, Valentine Chidi Basit, Abdul Waseh |
| description | Disclosed is a delayed release drug formulation for delivery of a drug to the colon comprising a particle with a core and a coating for the core, the core comprising a drug and the coating comprising a single layer of a mixture of a first material which is susceptible to attack by colonic bacteria and a second material which is a film-forming polymeric material having a pH threshold at about pH 6.5 or above, wherein the first material is carrageenan; and wherein the pH threshold of the second material is the pH below which it is insoluble and at or above which it is soluble. |
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and wherein the pH threshold of the second material is the pH below which it is insoluble and at or above which it is soluble.</description><language>eng</language><subject>CHEMISTRY ; COMPOSITIONS BASED THEREON ; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC MACROMOLECULAR COMPOUNDS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230825&DB=EPODOC&CC=NZ&NR=785519A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230825&DB=EPODOC&CC=NZ&NR=785519A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Ibekwe, Valentine Chidi</creatorcontrib><creatorcontrib>Basit, Abdul Waseh</creatorcontrib><title>Colonic drug delivery formulation</title><description>Disclosed is a delayed release drug formulation for delivery of a drug to the colon comprising a particle with a core and a coating for the core, the core comprising a drug and the coating comprising a single layer of a mixture of a first material which is susceptible to attack by colonic bacteria and a second material which is a film-forming polymeric material having a pH threshold at about pH 6.5 or above, wherein the first material is carrageenan; 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| subjects | CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP |
| title | Colonic drug delivery formulation |
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