Solid pharmaceutical compositions for treating hcv
The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises l00 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutic...
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| creator | Garrett, Colleen Lander, Ute Asmus, Katharin Reul, Regina Naris, Marius Steitz, Benedikt Westedt, Ulrich Jayasankar, Adivaraha Hach, Harald Tong, Ping Kyeremateng, Samuel Siimon, Michael Gao, Yi Schneider, Katrin Zhu, Donghua Sever, Nancy Mueller, Thomas Obermiller, Constanze |
| description | The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises l00 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion. |
| format | Patent |
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In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises l00 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240531&DB=EPODOC&CC=NZ&NR=775565A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240531&DB=EPODOC&CC=NZ&NR=775565A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Garrett, Colleen</creatorcontrib><creatorcontrib>Lander, Ute</creatorcontrib><creatorcontrib>Asmus, Katharin</creatorcontrib><creatorcontrib>Reul, Regina</creatorcontrib><creatorcontrib>Naris, Marius</creatorcontrib><creatorcontrib>Steitz, Benedikt</creatorcontrib><creatorcontrib>Westedt, Ulrich</creatorcontrib><creatorcontrib>Jayasankar, Adivaraha</creatorcontrib><creatorcontrib>Hach, Harald</creatorcontrib><creatorcontrib>Tong, Ping</creatorcontrib><creatorcontrib>Kyeremateng, Samuel</creatorcontrib><creatorcontrib>Siimon, Michael</creatorcontrib><creatorcontrib>Gao, Yi</creatorcontrib><creatorcontrib>Schneider, Katrin</creatorcontrib><creatorcontrib>Zhu, Donghua</creatorcontrib><creatorcontrib>Sever, Nancy</creatorcontrib><creatorcontrib>Mueller, Thomas</creatorcontrib><creatorcontrib>Obermiller, Constanze</creatorcontrib><title>Solid pharmaceutical compositions for treating hcv</title><description>The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. 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In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises l00 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Solid pharmaceutical compositions for treating hcv |
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