New combination of active agents for the treatment of progressive fibrosing interstitial lung diseases (pf-ild)

The application refers to a novel combination treatment/ combination medicament for PF-ILD treatment, comprising as a first combination partner a therapeutically effective amount of Nintedanib or a pharmaceutically acceptable salt thereof and as a second combination partner a therapeutically effecti...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Nickolaus, Peter, Herrmann, Franziska, Wollin, Stefan
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Nickolaus, Peter
Herrmann, Franziska
Wollin, Stefan
description The application refers to a novel combination treatment/ combination medicament for PF-ILD treatment, comprising as a first combination partner a therapeutically effective amount of Nintedanib or a pharmaceutically acceptable salt thereof and as a second combination partner a therapeutically effective amount of a PDE4B -inhibitor of formula (I) wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms and wherein R is Cl and wherein R may be located either in the para-, meta- or ortho-position of Ring A, wherein S* is a sulphur atom that represents a chiral center or a pharmaceutically acceptable salt thereof. Hereby the second combination partner is preferably a therapeutically effective amount of the PDE4B-inhibitior of formula (III) or a pharmaceutically acceptable salt thereof.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_NZ762200A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>NZ762200A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_NZ762200A3</originalsourceid><addsrcrecordid>eNqFyrEKwkAMgOEuDqK-gmTUoVAq6CyiOHVycilpm2sD18txifr6tuDu9MPPt8ykog-0MjYc0FgCiANsjd8E2FMwBScJbCCwRGjjtGYSk_SJVGfnuEmiHHrgYJTU2Bg9-Nd0OlZCJYVddDn7br_OFg690ubXVba9XR-Xe05RatKILQWyunqejmVZFOfDX_AFmxRB7Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>New combination of active agents for the treatment of progressive fibrosing interstitial lung diseases (pf-ild)</title><source>esp@cenet</source><creator>Nickolaus, Peter ; Herrmann, Franziska ; Wollin, Stefan</creator><creatorcontrib>Nickolaus, Peter ; Herrmann, Franziska ; Wollin, Stefan</creatorcontrib><description>The application refers to a novel combination treatment/ combination medicament for PF-ILD treatment, comprising as a first combination partner a therapeutically effective amount of Nintedanib or a pharmaceutically acceptable salt thereof and as a second combination partner a therapeutically effective amount of a PDE4B -inhibitor of formula (I) wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms and wherein R is Cl and wherein R may be located either in the para-, meta- or ortho-position of Ring A, wherein S* is a sulphur atom that represents a chiral center or a pharmaceutically acceptable salt thereof. Hereby the second combination partner is preferably a therapeutically effective amount of the PDE4B-inhibitior of formula (III) or a pharmaceutically acceptable salt thereof.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20241025&amp;DB=EPODOC&amp;CC=NZ&amp;NR=762200A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20241025&amp;DB=EPODOC&amp;CC=NZ&amp;NR=762200A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Nickolaus, Peter</creatorcontrib><creatorcontrib>Herrmann, Franziska</creatorcontrib><creatorcontrib>Wollin, Stefan</creatorcontrib><title>New combination of active agents for the treatment of progressive fibrosing interstitial lung diseases (pf-ild)</title><description>The application refers to a novel combination treatment/ combination medicament for PF-ILD treatment, comprising as a first combination partner a therapeutically effective amount of Nintedanib or a pharmaceutically acceptable salt thereof and as a second combination partner a therapeutically effective amount of a PDE4B -inhibitor of formula (I) wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms and wherein R is Cl and wherein R may be located either in the para-, meta- or ortho-position of Ring A, wherein S* is a sulphur atom that represents a chiral center or a pharmaceutically acceptable salt thereof. Hereby the second combination partner is preferably a therapeutically effective amount of the PDE4B-inhibitior of formula (III) or a pharmaceutically acceptable salt thereof.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyrEKwkAMgOEuDqK-gmTUoVAq6CyiOHVycilpm2sD18txifr6tuDu9MPPt8ykog-0MjYc0FgCiANsjd8E2FMwBScJbCCwRGjjtGYSk_SJVGfnuEmiHHrgYJTU2Bg9-Nd0OlZCJYVddDn7br_OFg690ubXVba9XR-Xe05RatKILQWyunqejmVZFOfDX_AFmxRB7Q</recordid><startdate>20241025</startdate><enddate>20241025</enddate><creator>Nickolaus, Peter</creator><creator>Herrmann, Franziska</creator><creator>Wollin, Stefan</creator><scope>EVB</scope></search><sort><creationdate>20241025</creationdate><title>New combination of active agents for the treatment of progressive fibrosing interstitial lung diseases (pf-ild)</title><author>Nickolaus, Peter ; Herrmann, Franziska ; Wollin, Stefan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NZ762200A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Nickolaus, Peter</creatorcontrib><creatorcontrib>Herrmann, Franziska</creatorcontrib><creatorcontrib>Wollin, Stefan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Nickolaus, Peter</au><au>Herrmann, Franziska</au><au>Wollin, Stefan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>New combination of active agents for the treatment of progressive fibrosing interstitial lung diseases (pf-ild)</title><date>2024-10-25</date><risdate>2024</risdate><abstract>The application refers to a novel combination treatment/ combination medicament for PF-ILD treatment, comprising as a first combination partner a therapeutically effective amount of Nintedanib or a pharmaceutically acceptable salt thereof and as a second combination partner a therapeutically effective amount of a PDE4B -inhibitor of formula (I) wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms and wherein R is Cl and wherein R may be located either in the para-, meta- or ortho-position of Ring A, wherein S* is a sulphur atom that represents a chiral center or a pharmaceutically acceptable salt thereof. Hereby the second combination partner is preferably a therapeutically effective amount of the PDE4B-inhibitior of formula (III) or a pharmaceutically acceptable salt thereof.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_NZ762200A
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title New combination of active agents for the treatment of progressive fibrosing interstitial lung diseases (pf-ild)
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T02%3A57%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Nickolaus,%20Peter&rft.date=2024-10-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ENZ762200A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true