Ocular formulations for drug-delivery and protection of the anterior segment of the eye

The present application relates to topical formulations comprising Compound-I, or its free base, and a second active agent selected from nicotinic acid, nicotinamide, and vitamin K, and a combination thereof, for treating ocular neovascularization. The present application also relates to pharmaceuti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bingaman, David P, Wax, Martin B, Chaney, Paul G
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present application relates to topical formulations comprising Compound-I, or its free base, and a second active agent selected from nicotinic acid, nicotinamide, and vitamin K, and a combination thereof, for treating ocular neovascularization. The present application also relates to pharmaceutical compositions comprising particles of Compound-I or its free base, and suspension formulations compring the particle compositions of Compound-I or its free base.