Materials and methods relating to linkers for use in protein drug conjugates

The present invention relates to protein drug conjugates, methods of manufacturing the same and their use in therapy. In particular, the present invention relates to protein drug conjugates comprising a globular protein, an improved linker and a drug for use in targeted drug delivery applications. T...

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Hauptverfasser: Baxter, Anthony David, Thirlway, Jenny, Mansell, David James, Mysliwy, Justyna Helena, Birchall, Christopher Michael
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creator Baxter, Anthony David
Thirlway, Jenny
Mansell, David James
Mysliwy, Justyna Helena
Birchall, Christopher Michael
description The present invention relates to protein drug conjugates, methods of manufacturing the same and their use in therapy. In particular, the present invention relates to protein drug conjugates comprising a globular protein, an improved linker and a drug for use in targeted drug delivery applications. The improved linker comprises a vinylpyridine motif.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Materials and methods relating to linkers for use in protein drug conjugates
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