Spirocyclic inhibitors of cathepsin c

This invention relates to a compound of formula (I) wherein A and Cy have one of the meanings as indicated in the specification and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same and methods of using the same as agents for treatment and/or prevention of disea...

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Hauptverfasser: Grauert, Matthias, Vintonyak, Viktor, Pautsch, Alexander, Grundl, Marc
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creator Grauert, Matthias
Vintonyak, Viktor
Pautsch, Alexander
Grundl, Marc
description This invention relates to a compound of formula (I) wherein A and Cy have one of the meanings as indicated in the specification and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Spirocyclic inhibitors of cathepsin c
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