Human antibodies that bind human il-12 and methods for producing

Disclosed is an article of manufacture comprising a pre-filled syringe which comprises 0.1-250 mg/mL of a human antibody, or antigen-binding portion thereof, that binds to human IL-12, formulated in a buffer comprising 1-50 mM L-histidine at pH 5.0-7.0.

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Bibliographische Detailangaben
Hauptverfasser:	VENTURINI AMY, KAYMAKCALAN ZEHRA, TRACEY DANIEL E, VELDMAN GEERTRUIDA M, DUNCAN ALEXANDER R, WHITE MICHAEL, SMITH STEPHEN, DO FOU SARAH L, SAKORAFAS PAUL, SALFELD JOCHEN G, MYLES ANGELA, FRIEDRICH STUART, ROGUSKA MICHAEL, PASKIND MICHAEL, WIDOM ANGELA M, HALTET THOR LAS, LABKOVSKY BORIS, DERBYSHIRE ELAINE J, BANERJEE SUBHASHIS, WARNE NICHOLAS W, CARMEN SARA
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed is an article of manufacture comprising a pre-filled syringe which comprises 0.1-250 mg/mL of a human antibody, or antigen-binding portion thereof, that binds to human IL-12, formulated in a buffer comprising 1-50 mM L-histidine at pH 5.0-7.0.