Pharmaceutical compositions of co-crystals of tramadol and coxibs

Pharmaceutical compositions of co-crystals of tramadol and coxibs

Disclosed herein are oral pharmaceutical compositions comprising co-crystals of tramadol and celecoxib and a solubility enhancer polymer, processes for preparation of the same and their use as medicaments, more particularly for the treatment of pain. In one embodiment the solubility enhancer polymer...

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Hauptverfasser: SOLER RANZANI LUIS, FALIVENE ALDEA ALBERT
Format: Patent
Sprache:eng
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator SOLER RANZANI LUIS
FALIVENE ALDEA ALBERT
description Disclosed herein are oral pharmaceutical compositions comprising co-crystals of tramadol and celecoxib and a solubility enhancer polymer, processes for preparation of the same and their use as medicaments, more particularly for the treatment of pain. In one embodiment the solubility enhancer polymer is selected from polyvinyl caprolactam-polyvinyl acetatepolyethylene glycol graft copolymer or from copovidone, povidone, cyclodextrin, polyethylene glycol and lauroyl macrogol-32 glycerides EP.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Pharmaceutical compositions of co-crystals of tramadol and coxibs
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