Co-crystals of VX-950 (telaprevir) and other components, and pharmaceutical compositions comprising the same
Disclosed is a co-crystal comprising (1S,3aR,6aS)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-1-carboxamide (Telaprevir) and 4-hydroxybenzoic acid.
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| creator | BHISETTI, GOVINDA, RAO JURKAUSKAS, VALDAS CONNELLY, PATRICK, R JOHNSTON, STEVE KADIYALA, IRINA ZHANG, YUEGANG ROSE, PETER STAVROPOLUS, KATHY |
| description | Disclosed is a co-crystal comprising (1S,3aR,6aS)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-1-carboxamide (Telaprevir) and 4-hydroxybenzoic acid. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Co-crystals of VX-950 (telaprevir) and other components, and pharmaceutical compositions comprising the same |
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