NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID
Disclosed is a compound of formula (1) where the substituents are as disclosed in the description. Example of compound of formula (1) are: 2-[4'-(3"[18F]fluoropropoxy)phenyl]-6-methoxyimidazo[1,2-a] pyridine and 6-methoxy-2-[4'-(3"-p-toluenesulfonyloxypropoxy) phenyl] imidazo [1,...
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| creator | BOUVET, DENIS RAYMOND CHRISTOPHE STOREY, ANTHONY EAMON NAKAMURA, DAISAKU TANIFUJI, SHIGEYUKI HAYASHI, AKIO TAKASAKI, SHINYA |
| description | Disclosed is a compound of formula (1) where the substituents are as disclosed in the description. Example of compound of formula (1) are: 2-[4'-(3"[18F]fluoropropoxy)phenyl]-6-methoxyimidazo[1,2-a] pyridine and 6-methoxy-2-[4'-(3"-p-toluenesulfonyloxypropoxy) phenyl] imidazo [1,2-a] pyridine. Also disclosed is a low-toxic diagnostic agent for Alzheimer's disease comprising a compound of formula (1); a pharmaceutical composition comprising a compound of formula (1) and the use of a compound of formula (1) for the preparation of a composition or agent. |
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Example of compound of formula (1) are: 2-[4'-(3"[18F]fluoropropoxy)phenyl]-6-methoxyimidazo[1,2-a] pyridine and 6-methoxy-2-[4'-(3"-p-toluenesulfonyloxypropoxy) phenyl] imidazo [1,2-a] pyridine. Also disclosed is a low-toxic diagnostic agent for Alzheimer's disease comprising a compound of formula (1); a pharmaceutical composition comprising a compound of formula (1) and the use of a compound of formula (1) for the preparation of a composition or agent.</description><language>eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEASUREMENT OF NUCLEAR OR X-RADIATION ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; TESTING</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120112&DB=EPODOC&CC=NZ&NR=574164A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120112&DB=EPODOC&CC=NZ&NR=574164A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BOUVET, DENIS RAYMOND CHRISTOPHE</creatorcontrib><creatorcontrib>STOREY, ANTHONY EAMON</creatorcontrib><creatorcontrib>NAKAMURA, DAISAKU</creatorcontrib><creatorcontrib>TANIFUJI, SHIGEYUKI</creatorcontrib><creatorcontrib>HAYASHI, AKIO</creatorcontrib><creatorcontrib>TAKASAKI, SHINYA</creatorcontrib><title>NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID</title><description>Disclosed is a compound of formula (1) where the substituents are as disclosed in the description. 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Example of compound of formula (1) are: 2-[4'-(3"[18F]fluoropropoxy)phenyl]-6-methoxyimidazo[1,2-a] pyridine and 6-methoxy-2-[4'-(3"-p-toluenesulfonyloxypropoxy) phenyl] imidazo [1,2-a] pyridine. Also disclosed is a low-toxic diagnostic agent for Alzheimer's disease comprising a compound of formula (1); a pharmaceutical composition comprising a compound of formula (1) and the use of a compound of formula (1) for the preparation of a composition or agent.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEASUREMENT OF NUCLEAR OR X-RADIATION MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING |
| title | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID |
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