Pharmaceutical composition comprising N-[(1-n-butyl-4-piperidinyl) methyl]-3,4-dihydro-2H-[1, 3]oxazino[3, 2-a]indole-10-carboxamide or salt, and process for preparing thereof comprising dry granulation

A process for preparing a pharmaceutical composition comprising N-[(1-nbutyl-4-piperidinyl) methyl]-3, 4-dihydro-2H-[1, 3]oxazino[3, 2-a]indole-10-carboxamide (SB 207266) in combination with one or more pharmaceutically acceptable excipients. The process comprising forming part or all of the SB 2072...

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Hauptverfasser:	BUXTON, PHILIP CHRISTOPHER, THOMSON, SEONA, VAN SCHIE, DIRK MARINUS JOHANNES, GROVES, SHARON ELIZABETH, YEATES, KENNETH TREVOR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	BUXTON, PHILIP CHRISTOPHER THOMSON, SEONA VAN SCHIE, DIRK MARINUS JOHANNES GROVES, SHARON ELIZABETH YEATES, KENNETH TREVOR
description	A process for preparing a pharmaceutical composition comprising N-[(1-nbutyl-4-piperidinyl) methyl]-3, 4-dihydro-2H-[1, 3]oxazino[3, 2-a]indole-10-carboxamide (SB 207266) in combination with one or more pharmaceutically acceptable excipients. The process comprising forming part or all of the SB 207266 into granules by a dry granulation process. Wherein the SB 207266 is present in the composition in at least 4 % by weight of the composition.
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	Pharmaceutical composition comprising N-[(1-n-butyl-4-piperidinyl) methyl]-3,4-dihydro-2H-[1, 3]oxazino[3, 2-a]indole-10-carboxamide or salt, and process for preparing thereof comprising dry granulation
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