Treatment of fungal infections with polyene or beta glucan synthase inhibitor antifungals combined with anti HSP90 antibodies

The use of a composition comprising an antibody or an antigen binding fragment thereof specific for one or more epitopes of a fungal stress protein and an antifungal agent comprising at least one of the group consisting of a polyene antifungal agent and an echinocandin antiftngal agent in a method o...

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1. Verfasser: BURNIE, JAMES PETER
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creator BURNIE, JAMES PETER
description The use of a composition comprising an antibody or an antigen binding fragment thereof specific for one or more epitopes of a fungal stress protein and an antifungal agent comprising at least one of the group consisting of a polyene antifungal agent and an echinocandin antiftngal agent in a method of manufacture of a medicarnent for the treatment of fungal infections, wherein the fungus causing said fingal infection is resistant to said antifungal agent per se.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
title Treatment of fungal infections with polyene or beta glucan synthase inhibitor antifungals combined with anti HSP90 antibodies
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