Recombinant and/or pure preparations of H. pylori polypeptides and nucleic acids which are useful for diagnostics and vaccines

Recombinant or substantially pure preparations of H. pylori polypeptides are described. The nucleic acids encoding the polypeptides also are described. The said polypeptides are useful for diagnostics and vaccine compositions for the prevention or treatment of a H. pylori infection. This invention a...

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Hauptverfasser: BERGLINDH, O THOMAS, MELLGARD, BJORN L, SMITH, DOUGLAS
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MELLGARD, BJORN L
SMITH, DOUGLAS
description Recombinant or substantially pure preparations of H. pylori polypeptides are described. The nucleic acids encoding the polypeptides also are described. The said polypeptides are useful for diagnostics and vaccine compositions for the prevention or treatment of a H. pylori infection. This invention also incorporates a drug-screening assay by contacting a test compound with the purified H. pylori polypeptide and a method for the detection of H. pylori by using the purified fragment as a hybridisation probe.
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The nucleic acids encoding the polypeptides also are described. The said polypeptides are useful for diagnostics and vaccine compositions for the prevention or treatment of a H. pylori infection. This invention also incorporates a drug-screening assay by contacting a test compound with the purified H. pylori polypeptide and a method for the detection of H. pylori by using the purified fragment as a hybridisation probe.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
THEIR PREPARATION OR CHEMICAL WORKING-UP
USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS
VINEGAR
WINE
title Recombinant and/or pure preparations of H. pylori polypeptides and nucleic acids which are useful for diagnostics and vaccines
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