Fremgangsmåte for fremstilling av (E)-2-fluormethylen-4-(4-fluorfenyl)butylamin og alkalimetallsalter av diformylamid

Fremgangsmåte for fremstilling av (E)-2-fluormethylen-4-(4-fluorfenyl)butylamin og alkalimetallsalter av diformylamid

The present invention relates to a novel process for preparing (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, also known in the art as (E)-(p-fluorophenethyl)-3-fluoroallylamine, and novel intermediates thereof (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane is useful as an irrev...

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Hauptverfasser: HENTON, DANIEL RANDOLPH, VOSEJPKA, PAUL CHARLES, EVANS, JONATHAN CHARLES, GORALSKI, CHRISTIAN THOMAS, RAND, CYNTHIA LUCILLE
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator HENTON, DANIEL RANDOLPH
VOSEJPKA, PAUL CHARLES
EVANS, JONATHAN CHARLES
GORALSKI, CHRISTIAN THOMAS
RAND, CYNTHIA LUCILLE
description The present invention relates to a novel process for preparing (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, also known in the art as (E)-(p-fluorophenethyl)-3-fluoroallylamine, and novel intermediates thereof (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane is useful as an irreversible inhibitor of monoamine oxidase.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Fremgangsmåte for fremstilling av (E)-2-fluormethylen-4-(4-fluorfenyl)butylamin og alkalimetallsalter av diformylamid
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