PYRIDINYL-KINOLONFORBINDELSER, DERES FREMSTILLING OG BRUK
Fluorinated 1-cyclopropyl-7-(substituted-pyridinyl)-1,4-dihydro-4-oxo-3-quinolinec arboxylic acids of the formula wherein R is hydrogen, R min and R sec are hydrogen or fluoro, and Z is 3- or 4-pyridinyl substituted by alkyl groups or substituted alkyl groups, are superior antibacterial agents. They...
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| creator | LESHER, GEORGE YOHE REUMAN, MICHAEL SINGH, BALDEV DAUM, SOL JACOB |
| description | Fluorinated 1-cyclopropyl-7-(substituted-pyridinyl)-1,4-dihydro-4-oxo-3-quinolinec arboxylic acids of the formula wherein R is hydrogen, R min and R sec are hydrogen or fluoro, and Z is 3- or 4-pyridinyl substituted by alkyl groups or substituted alkyl groups, are superior antibacterial agents. They are prepared via a coupling reaction between the corresponding esters (R = alkyl) having a halo group in the 7-position and a substituted (trialkylstannyl)pyridine. |
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They are prepared via a coupling reaction between the corresponding esters (R = alkyl) having a halo group in the 7-position and a substituted (trialkylstannyl)pyridine.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PYRIDINYL-KINOLONFORBINDELSER, DERES FREMSTILLING OG BRUK |
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