Farmasøytisk sammensetning inneholdende en tetrahydrofolsyre

Farmasøytisk sammensetning inneholdende en tetrahydrofolsyre

The present invention relates to solid oral unit dosage form, in particular to oral contraceptives, comprising i) granules comprising a progestogen, such as drospirenone; an estrogen, such as ethinylestradiol; and microcrystalline cellulose and, ii) a pharmaceutically acceptable salt of 5-methyl-(6S...

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1. Verfasser: King, Kristina
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Sprache:nor
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator King, Kristina
description The present invention relates to solid oral unit dosage form, in particular to oral contraceptives, comprising i) granules comprising a progestogen, such as drospirenone; an estrogen, such as ethinylestradiol; and microcrystalline cellulose and, ii) a pharmaceutically acceptable salt of 5-methyl-(6S)-tetrahydrofolic acid. The compositions of the invention provide good stability of the tetrahydrofolic acid upon storage while still ensuring a fast and reliable release of the estrogen and the progestogen present in the composition.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Farmasøytisk sammensetning inneholdende en tetrahydrofolsyre
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