Anvendelse av polyoler for å oppnå stabile polymorfe former av rifaximin

Anvendelse av polyoler for å oppnå stabile polymorfe former av rifaximin

Polyols stabilize polymorphous form of rifaximin, in particular the ² form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ² is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations...

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Hauptverfasser: Bottoni, Giuseppe, Maffei, Paola, Viscomi, Claudio Giuseppe, Bachetti, Milena
Format: Patent
Sprache:nor
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Bottoni, Giuseppe
Maffei, Paola
Viscomi, Claudio Giuseppe
Bachetti, Milena
description Polyols stabilize polymorphous form of rifaximin, in particular the ² form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ² is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations constituted by pure and stable polymorphous forms able to give a pharmaceutical product is described.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Anvendelse av polyoler for å oppnå stabile polymorfe former av rifaximin
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