Fremgangsmåte ved fremstilling av et klodronatpreparat

Fremgangsmåte ved fremstilling av et klodronatpreparat

PCT No. PCT/FI94/00509 Sec. 371 Date Aug. 6, 1996 Sec. 102(e) Date Aug. 6, 1996 PCT Filed Nov. 11, 1994 PCT Pub. No. WO95/13054 PCT Pub. Date May 18, 1995The object of the invention is a process for preparing a clodronate preparation. The process is characterized in that clodronate is crystallized a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: POHJALA, ESKO, LEHMUSSAARI, KARI, NUPPONEN, HEIKKI
Format: Patent
Sprache:nor
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator POHJALA, ESKO
LEHMUSSAARI, KARI
NUPPONEN, HEIKKI
description PCT No. PCT/FI94/00509 Sec. 371 Date Aug. 6, 1996 Sec. 102(e) Date Aug. 6, 1996 PCT Filed Nov. 11, 1994 PCT Pub. No. WO95/13054 PCT Pub. Date May 18, 1995The object of the invention is a process for preparing a clodronate preparation. The process is characterized in that clodronate is crystallized as disodium clodronate tetrahydrate from an aqueous solution of disodium clodronate; the resulting disodium clodronate tetrahydrate is dry granulated by compressing in such a way that the crystal structure of the disodium clodronate tetrahydrate is preserved and by crumbling and screening the mass to granules of a sutiable size, the dry granulated disodium clodronate tetrahydrate is optionally mixed with suitable excipients, such as filling agents and gliding agents and, if necessary, disintegrants.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_NO312938BB1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>NO312938BB1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_NO312938BB13</originalsourceid><addsrcrecordid>eNrjZDB3K0rNTU_MSy_OPby0JFWhLDVFIQ0oVFySmZOTmZeukFimkFqikJ2Tn1KUn5dYUlCUWpBYlFjCw8CalphTnMoLpbkZFNxcQ5w9dFML8uNTiwsSk1PzUkvi_fyNDY0sjS2cnAyNiVACABfWLwQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Fremgangsmåte ved fremstilling av et klodronatpreparat</title><source>esp@cenet</source><creator>POHJALA, ESKO ; LEHMUSSAARI, KARI ; NUPPONEN, HEIKKI</creator><creatorcontrib>POHJALA, ESKO ; LEHMUSSAARI, KARI ; NUPPONEN, HEIKKI</creatorcontrib><description>PCT No. PCT/FI94/00509 Sec. 371 Date Aug. 6, 1996 Sec. 102(e) Date Aug. 6, 1996 PCT Filed Nov. 11, 1994 PCT Pub. No. WO95/13054 PCT Pub. Date May 18, 1995The object of the invention is a process for preparing a clodronate preparation. The process is characterized in that clodronate is crystallized as disodium clodronate tetrahydrate from an aqueous solution of disodium clodronate; the resulting disodium clodronate tetrahydrate is dry granulated by compressing in such a way that the crystal structure of the disodium clodronate tetrahydrate is preserved and by crumbling and screening the mass to granules of a sutiable size, the dry granulated disodium clodronate tetrahydrate is optionally mixed with suitable excipients, such as filling agents and gliding agents and, if necessary, disintegrants.</description><edition>7</edition><language>nor</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20020722&amp;DB=EPODOC&amp;CC=NO&amp;NR=312938B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20020722&amp;DB=EPODOC&amp;CC=NO&amp;NR=312938B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>POHJALA, ESKO</creatorcontrib><creatorcontrib>LEHMUSSAARI, KARI</creatorcontrib><creatorcontrib>NUPPONEN, HEIKKI</creatorcontrib><title>Fremgangsmåte ved fremstilling av et klodronatpreparat</title><description>PCT No. PCT/FI94/00509 Sec. 371 Date Aug. 6, 1996 Sec. 102(e) Date Aug. 6, 1996 PCT Filed Nov. 11, 1994 PCT Pub. No. WO95/13054 PCT Pub. Date May 18, 1995The object of the invention is a process for preparing a clodronate preparation. The process is characterized in that clodronate is crystallized as disodium clodronate tetrahydrate from an aqueous solution of disodium clodronate; the resulting disodium clodronate tetrahydrate is dry granulated by compressing in such a way that the crystal structure of the disodium clodronate tetrahydrate is preserved and by crumbling and screening the mass to granules of a sutiable size, the dry granulated disodium clodronate tetrahydrate is optionally mixed with suitable excipients, such as filling agents and gliding agents and, if necessary, disintegrants.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB3K0rNTU_MSy_OPby0JFWhLDVFIQ0oVFySmZOTmZeukFimkFqikJ2Tn1KUn5dYUlCUWpBYlFjCw8CalphTnMoLpbkZFNxcQ5w9dFML8uNTiwsSk1PzUkvi_fyNDY0sjS2cnAyNiVACABfWLwQ</recordid><startdate>20020722</startdate><enddate>20020722</enddate><creator>POHJALA, ESKO</creator><creator>LEHMUSSAARI, KARI</creator><creator>NUPPONEN, HEIKKI</creator><scope>EVB</scope></search><sort><creationdate>20020722</creationdate><title>Fremgangsmåte ved fremstilling av et klodronatpreparat</title><author>POHJALA, ESKO ; LEHMUSSAARI, KARI ; NUPPONEN, HEIKKI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NO312938BB13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>nor</language><creationdate>2002</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>POHJALA, ESKO</creatorcontrib><creatorcontrib>LEHMUSSAARI, KARI</creatorcontrib><creatorcontrib>NUPPONEN, HEIKKI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>POHJALA, ESKO</au><au>LEHMUSSAARI, KARI</au><au>NUPPONEN, HEIKKI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Fremgangsmåte ved fremstilling av et klodronatpreparat</title><date>2002-07-22</date><risdate>2002</risdate><abstract>PCT No. PCT/FI94/00509 Sec. 371 Date Aug. 6, 1996 Sec. 102(e) Date Aug. 6, 1996 PCT Filed Nov. 11, 1994 PCT Pub. No. WO95/13054 PCT Pub. Date May 18, 1995The object of the invention is a process for preparing a clodronate preparation. The process is characterized in that clodronate is crystallized as disodium clodronate tetrahydrate from an aqueous solution of disodium clodronate; the resulting disodium clodronate tetrahydrate is dry granulated by compressing in such a way that the crystal structure of the disodium clodronate tetrahydrate is preserved and by crumbling and screening the mass to granules of a sutiable size, the dry granulated disodium clodronate tetrahydrate is optionally mixed with suitable excipients, such as filling agents and gliding agents and, if necessary, disintegrants.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language nor
recordid cdi_epo_espacenet_NO312938BB1
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Fremgangsmåte ved fremstilling av et klodronatpreparat
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T23%3A29%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=POHJALA,%20ESKO&rft.date=2002-07-22&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ENO312938BB1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true