Fremgangsmåte for fremstilling av N-acetyl- neuraminsyrederivater
PCT No. PCT/EP94/01940 Sec. 371 Date Mar. 8, 1996 Sec. 102(e) Date Mar. 8, 1996 PCT Filed Jun. 15, 1994 PCT Pub. No. WO95/00503 PCT Pub. Date Jan. 5, 1995The invention provides a method for the preparation of the compound of formula(I) (I) which comprises catalytic hydrogenolysis of a compound of fo...
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| creator | SEARLE, ANDREW DAVID WILLIAMSON, CHRISTOPHER |
| description | PCT No. PCT/EP94/01940 Sec. 371 Date Mar. 8, 1996 Sec. 102(e) Date Mar. 8, 1996 PCT Filed Jun. 15, 1994 PCT Pub. No. WO95/00503 PCT Pub. Date Jan. 5, 1995The invention provides a method for the preparation of the compound of formula(I) (I) which comprises catalytic hydrogenolysis of a compound of formula (II) (II) (wherein R is H or a C1-4alkyl group and R1 is H or a hydroxyl protecting group for example an acyl group such as acetyl) in aqueous formic acid followed, where necessary, by hydrolysis. |
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| subjects | APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING |
| title | Fremgangsmåte for fremstilling av N-acetyl- neuraminsyrederivater |
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