Mitotiske kinesininhibitorer og fremgangsmater for anvendelse derav

Denne oppfinnelsen vedrører inhibitorer av mitotiske kinesiner, særlig KSP, og fremgangsmåter for fremstilling av disse inhibitorene. Oppfinnelsen tilveiebringer også farmasøytiske preparater som omfatter inhibitorene ifølge oppfinnelsen, og fremgangsmåter for anvendelse av inhibitorene og de farmas...

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Hauptverfasser: ROBINSON JOHN E, ALLEN SHELLEY, VOEGTLI WALTER CHARLES, HANS JEREMY, LAIRD ELLEN, WALLACE ELI M, LYSSIKATOS JOSEPH P, ZHAO QIAN, DELISLE ROBERT KIRK, CORRETTE CHRISTOPHER P
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creator ROBINSON JOHN E
ALLEN SHELLEY
VOEGTLI WALTER CHARLES
HANS JEREMY
LAIRD ELLEN
WALLACE ELI M
LYSSIKATOS JOSEPH P
ZHAO QIAN
DELISLE ROBERT KIRK
CORRETTE CHRISTOPHER P
description Denne oppfinnelsen vedrører inhibitorer av mitotiske kinesiner, særlig KSP, og fremgangsmåter for fremstilling av disse inhibitorene. Oppfinnelsen tilveiebringer også farmasøytiske preparater som omfatter inhibitorene ifølge oppfinnelsen, og fremgangsmåter for anvendelse av inhibitorene og de farmasøytiske preparatene ved behandling og profylakse av forskjellige forstyrrelser. This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Mitotiske kinesininhibitorer og fremgangsmater for anvendelse derav
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