C1-symmetriske bisfosfin-ligander og deres anvendelse i assymetrisk syntese av pre-gabalin

Det beskrives materiale og fremgangsmåter for å fremstille (S)-(+)-3-(aminometyl)-5-metyl-heksanoisk syre og strukturelt beslektede forbindelser via enantioselektiv hydrogenering av prokirale olefiner. Fremgangsmåtene benytter nye kirale katalysatorer, som inkluderer C1-symmetriske bifosfinligander...

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Hauptverfasser:	WU HE PING, HOGE GARRETT, BAO JIAN, KISSEL WILLIAM, BEYLIN VLADIMIR GENUKH, PFLUM DEREK ANDREW, GREENE DEREK JOSEPH, MARLATT MARK EUGENE
Format:	Patent
Sprache:	nor
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING
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