Conjugates of TC complexes and targeting moiettes and their use in mri diagnostic
Foreliggende oppfinnelse gjelder forbedredem Tc radiometallkompleks sammensetninger av azo-diamin-dioksim-ligander, sammen med de radiofarmasøytiske preparater som inneholder dem, samt sett for fremstilling av de radiofarmasøytiske produktene.Det er påvist at teknetium-metallkomplekserings kjemien f...
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| creator | BRAUERS GEORG |
| description | Foreliggende oppfinnelse gjelder forbedredem Tc radiometallkompleks sammensetninger av azo-diamin-dioksim-ligander, sammen med de radiofarmasøytiske preparater som inneholder dem, samt sett for fremstilling av de radiofarmasøytiske produktene.Det er påvist at teknetium-metallkomplekserings kjemien for azo-diamindioksim målsøkendemolekyl kelator konjugater gir opphav til en lang rekke teknetiumarter. Foreliggende oppfinnelse tilveiebringer en forbedret azo-diamin-dioksim konjugat teknetium metallkomplekssammensetning,. der tilstedeværelsen av de mindre ønskelige teknetium-artene er undertrykt.
The present invention relates to improved Tc radiometal complex compositions of aza-diaminedioxime ligands, together with radiopharmaceutical preparations containing them, and kits for the preparation of the radiopharmaceuticals. The technetium metal complexation chemistry of aza-diaminedioxime-targeting molecule chelator conjugates is shown to give rise to a multiplicity of technetium species. The present invention provides an improved aza-diaminedioxime conjugate technetium metal complex composition in which the presence of the less desirable technetium species is suppressed. |
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The present invention relates to improved Tc radiometal complex compositions of aza-diaminedioxime ligands, together with radiopharmaceutical preparations containing them, and kits for the preparation of the radiopharmaceuticals. The technetium metal complexation chemistry of aza-diaminedioxime-targeting molecule chelator conjugates is shown to give rise to a multiplicity of technetium species. The present invention provides an improved aza-diaminedioxime conjugate technetium metal complex composition in which the presence of the less desirable technetium species is suppressed.</description><edition>7</edition><language>nor</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050627&DB=EPODOC&CC=NO&NR=20051811L$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050627&DB=EPODOC&CC=NO&NR=20051811L$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BRAUERS GEORG</creatorcontrib><title>Conjugates of TC complexes and targeting moiettes and their use in mri diagnostic</title><description>Foreliggende oppfinnelse gjelder forbedredem Tc radiometallkompleks sammensetninger av azo-diamin-dioksim-ligander, sammen med de radiofarmasøytiske preparater som inneholder dem, samt sett for fremstilling av de radiofarmasøytiske produktene.Det er påvist at teknetium-metallkomplekserings kjemien for azo-diamindioksim målsøkendemolekyl kelator konjugater gir opphav til en lang rekke teknetiumarter. Foreliggende oppfinnelse tilveiebringer en forbedret azo-diamin-dioksim konjugat teknetium metallkomplekssammensetning,. der tilstedeværelsen av de mindre ønskelige teknetium-artene er undertrykt.
The present invention relates to improved Tc radiometal complex compositions of aza-diaminedioxime ligands, together with radiopharmaceutical preparations containing them, and kits for the preparation of the radiopharmaceuticals. The technetium metal complexation chemistry of aza-diaminedioxime-targeting molecule chelator conjugates is shown to give rise to a multiplicity of technetium species. The present invention provides an improved aza-diaminedioxime conjugate technetium metal complex composition in which the presence of the less desirable technetium species is suppressed.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNirEKwjAQQLs4iPoP5wcIjSK4B8WhKEL3cqTX9KS5hOQKfr4Oujs93uMtq4eN8pw9KhWIA7QWXAxpotfHUXpQzJ6UxUOITKq_PBJnmAsBC4TM0DN6iUXZravFgFOhzZerans5t_a6oxQ7KgkdCWl3u-_r-mhOxjTN4Z_nDaacN5M</recordid><startdate>20050627</startdate><enddate>20050627</enddate><creator>BRAUERS GEORG</creator><scope>EVB</scope></search><sort><creationdate>20050627</creationdate><title>Conjugates of TC complexes and targeting moiettes and their use in mri diagnostic</title><author>BRAUERS GEORG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NO20051811LL3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>nor</language><creationdate>2005</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>BRAUERS GEORG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BRAUERS GEORG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Conjugates of TC complexes and targeting moiettes and their use in mri diagnostic</title><date>2005-06-27</date><risdate>2005</risdate><abstract>Foreliggende oppfinnelse gjelder forbedredem Tc radiometallkompleks sammensetninger av azo-diamin-dioksim-ligander, sammen med de radiofarmasøytiske preparater som inneholder dem, samt sett for fremstilling av de radiofarmasøytiske produktene.Det er påvist at teknetium-metallkomplekserings kjemien for azo-diamindioksim målsøkendemolekyl kelator konjugater gir opphav til en lang rekke teknetiumarter. Foreliggende oppfinnelse tilveiebringer en forbedret azo-diamin-dioksim konjugat teknetium metallkomplekssammensetning,. der tilstedeværelsen av de mindre ønskelige teknetium-artene er undertrykt.
The present invention relates to improved Tc radiometal complex compositions of aza-diaminedioxime ligands, together with radiopharmaceutical preparations containing them, and kits for the preparation of the radiopharmaceuticals. The technetium metal complexation chemistry of aza-diaminedioxime-targeting molecule chelator conjugates is shown to give rise to a multiplicity of technetium species. The present invention provides an improved aza-diaminedioxime conjugate technetium metal complex composition in which the presence of the less desirable technetium species is suppressed.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| title | Conjugates of TC complexes and targeting moiettes and their use in mri diagnostic |
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