Aminonikotinatderivater som glukokinase (GLK) modulatorer

The invention is related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relat...

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Hauptverfasser: JONES CLIFFORD DAVID, MCKERRECHER DARREN, GASKIN HAROLD, JAMES ROGER, HARGREAVES RODNEY BRIAN, HAYTER BARRY RAYMOND, ALLEN JOANNE VICTORIA, JOHNSTONE CRAIG, CURRIE GORDON, CAULKETT PETER WILLIAM RODNEY
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creator JONES CLIFFORD DAVID
MCKERRECHER DARREN
GASKIN HAROLD
JAMES ROGER
HARGREAVES RODNEY BRIAN
HAYTER BARRY RAYMOND
ALLEN JOANNE VICTORIA
JOHNSTONE CRAIG
CURRIE GORDON
CAULKETT PETER WILLIAM RODNEY
description The invention is related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Aminonikotinatderivater som glukokinase (GLK) modulatorer
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