Aromatisk sulfonhydroksamsyre-metalloproteaseinhibitor

A treatment process is disclosed that comprises administering an effective amount of an aromatic sulfone hydroxamic acid that exhibits excellent inhibitory activity of one or more matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9 and MMP-13, while exhibiting substantially less inhibition at...

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Hauptverfasser:	TOLLEFSON, MICHAEL B, FRESKOS, JOHN N, GETMAN, DANIEL P, RICO, JOSEPH G, FOBIAN, YVETTE M, DECRESCENZO, GARY A, KOLODZIEJ, STEPHEN A, LI, MADELEINE HUI, BEDELL, LOUIS J, MCDONALD, JOSEPH J, CARROLL, JEFFREY N, HOCKERMAN, SUSAN L, HOWARD, SUSAN C, BOEHM, TERRI L, STEHLE, NATHAN W, BECKER, DANIEL P, VERNIER, WILLIAM F, VILLAMIL, CLARA I, MISCHKE, DEBORAH A, BARTA, THOMAS E
Format:	Patent
Sprache:	nor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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