DNA-vektor for ekspresjon av desulfatohirudin i gjær eller E.coli samt fremgangsmåte for fremstilling av desulfatohirudin og salter derav
The invention relates to DNA sequences which code for the amino-acid sequence of the thrombin inhibitor hirudin, to hybrid vectors containing such DNA sequences, to host cells transformed with such hybrid vectors, to polypeptides produced by such transformed host cells and having thrombin inhibitory...
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| creator | MEYHACK, BERND RINK, HANS GRUTTER, MARKUS GERHARD LIERSCH, MANFRED MARKI, WALTER |
| description | The invention relates to DNA sequences which code for the amino-acid sequence of the thrombin inhibitor hirudin, to hybrid vectors containing such DNA sequences, to host cells transformed with such hybrid vectors, to polypeptides produced by such transformed host cells and having thrombin inhibitory activity, to processes for preparing these DNA sequences, hybrid vectors and transformed host cells and processes for preparing these thrombin inhibitors using the transformed host cells. The hirudin compounds have valuable pharmacological properties. |
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RINK, HANS ; GRUTTER, MARKUS GERHARD ; LIERSCH, MANFRED ; MARKI, WALTER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NO177433BB3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>nor</language><creationdate>1995</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>DERIVATIVES THEREOF</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>SUGARS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>MEYHACK, BERND</creatorcontrib><creatorcontrib>RINK, HANS</creatorcontrib><creatorcontrib>GRUTTER, MARKUS GERHARD</creatorcontrib><creatorcontrib>LIERSCH, MANFRED</creatorcontrib><creatorcontrib>MARKI, WALTER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MEYHACK, BERND</au><au>RINK, HANS</au><au>GRUTTER, MARKUS GERHARD</au><au>LIERSCH, MANFRED</au><au>MARKI, WALTER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DNA-vektor for ekspresjon av desulfatohirudin i gjær eller E.coli samt fremgangsmåte for fremstilling av desulfatohirudin og salter derav</title><date>1995-06-06</date><risdate>1995</risdate><abstract>The invention relates to DNA sequences which code for the amino-acid sequence of the thrombin inhibitor hirudin, to hybrid vectors containing such DNA sequences, to host cells transformed with such hybrid vectors, to polypeptides produced by such transformed host cells and having thrombin inhibitory activity, to processes for preparing these DNA sequences, hybrid vectors and transformed host cells and processes for preparing these thrombin inhibitors using the transformed host cells. The hirudin compounds have valuable pharmacological properties.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS TESTING VINEGAR WINE |
| title | DNA-vektor for ekspresjon av desulfatohirudin i gjær eller E.coli samt fremgangsmåte for fremstilling av desulfatohirudin og salter derav |
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