FREMGANGSM TE FOR FREMSTILLING AV ET STABILISERT SAL-PREPARAT

FREMGANGSM TE FOR FREMSTILLING AV ET STABILISERT SAL-PREPARAT

New medicaments are aq. dispersions of one or more cellulose derivs. contg. salbutanol and/or one or more physiologically acceptable salts of salbutanol. Suitable cellulose derivs. are those which form an optically transparent or opalescent dispersion in water. Particularly pref. are ethylcellulose,...

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Hauptverfasser: GROOM, CHERYL VANESSA, PADFIELD, JOHN MALCOLM
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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PADFIELD, JOHN MALCOLM
description New medicaments are aq. dispersions of one or more cellulose derivs. contg. salbutanol and/or one or more physiologically acceptable salts of salbutanol. Suitable cellulose derivs. are those which form an optically transparent or opalescent dispersion in water. Particularly pref. are ethylcellulose, methylcellulose, ethylmethylcellulose, hydroxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethyl methylcellulose, hydroxypropylmethylcellulose, hydroxyethyl-ethyl cellulose and carboxymethyl cellulose and its salts. The cellulose deriv. is pref. used in a total amt. of at least 0.1% w/v. For oral formulations, the cellulose deriv. is pref. present in an amt. such as to give a viscosity of 5-10000 (esp. 10-100) cPs. Salbutanol or its salt is pref. present in an amt. of 1-4 (esp.2) mg. per 5 ml., expressed as salbutanol free base. The prepn. pref. has a pH of 3.5. Salbutanol is a beta-stimulant with improved stability.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title FREMGANGSM TE FOR FREMSTILLING AV ET STABILISERT SAL-PREPARAT
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