ANALOGIFREMGANGSMAATE FOR FREMSTILLING AV TERAPEUTISK AKTIVE 5-(LAVEREALKYL)-1,6-NAFTYRIDIN-2(1H)-ON-FORBINDELSER

Naphthyridines of formula (I) , where R is -alkyl, R min is hydrogen or methyl, R sec is hydrogen or alkyl, and Q is hydrogen, hydroxy, amino, cyano, carbamyl, carboxy or aminocarbamyl, are useful as cardiotonic agents (I, Q is hydrogen, hydroxy, amino, cyano or carbamyl) and/or intermediates theref...

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Bibliographische Detailangaben
Hauptverfasser: LESHER, GEORGE YOHE, SINGH, BALDEV
Format: Patent
Sprache:nor
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Zusammenfassung:Naphthyridines of formula (I) , where R is -alkyl, R min is hydrogen or methyl, R sec is hydrogen or alkyl, and Q is hydrogen, hydroxy, amino, cyano, carbamyl, carboxy or aminocarbamyl, are useful as cardiotonic agents (I, Q is hydrogen, hydroxy, amino, cyano or carbamyl) and/or intermediates therefor (I, Q is carboxy, aminocarbamyl, hydrogen, amino, cyano or carbamyl). Also shown are pyridinones of formula II where R and R min are as above and Q min is hydrogen or cyano, which are useful as cardiotonics (II, Q min is hydrogen) and/or intermediates (II, Q min is cyano or hydrogen). Processes for preparing the compounds of Formulas I and II are shown.