ANALOGIFREMGANGSM TE VED FREMSTILLING AV TERAPEUTISK VIRKSOMME 7-SUBSTITUERTE THEOFYLLINDERIVATER
Antitussive compounds of the formula I (I) or physiologically acceptable acid addition salts thereof are disclosed, where A stands for straight or branched chain C1-5 alkylene or R1 stands for straight or branched chain C1-10 alkyl, halogenoalkyl, hydroxyalkyl, C5-6 cycloalkyl, vinyl, 2-ethoxyethyl,...
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| creator | KISS, PAL VIRAG, SANDOR HEJA, GERGELY SEBESTYEN, GYULA KOVACS, GABOR GOENCZI, CSABA MINKER, EMIL SZUETS, TAMAS SZOMOR, MARIA PALOSI, ENDRE SZVOBODA, IDA KUN, JUDIT KORBONITS, DEZSO |
| description | Antitussive compounds of the formula I (I) or physiologically acceptable acid addition salts thereof are disclosed, where A stands for straight or branched chain C1-5 alkylene or R1 stands for straight or branched chain C1-10 alkyl, halogenoalkyl, hydroxyalkyl, C5-6 cycloalkyl, vinyl, 2-ethoxyethyl, carbonylalkyl or aminoalkyl of the formula wherein R stands for hydrogen or methyl, n is 0 to 3, R2 stands for hydrogen or straight or branched chain alkyl, R3 stands for hydrogen or straight or branched chain alkyl or, R2 and R3 together with the nitrogen atom may form a 5-6 membered ring, which ring can optionally contain an oxygen or a second nitrogen atom, the latter, optionally substituted by methyl or, R1 can stand for a phenyl group of the formula R4R5C6H3 wherein R4 and R5 represent independently hydrogen, chlorine, hydroxy, methoxy, ethoxy, methyl or amino or, R1 may further stand for hydroxy, in this case the compound of the formula I may exist according to the conditions in the form of tautomers of the formula Ia (Ia) or (Ib) and R1 may further stand for benzyl, 2,2-diphenylethyl or theophyllin-7-yl-methyl. |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_NO159794CC</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>NO159794CC</sourcerecordid><originalsourceid>FETCH-epo_espacenet_NO159794CC3</originalsourceid><addsrcrecordid>eNqFi70KwjAYALM4iPoM5gU6iErp-Jl-SUObRPIHTiVInEQL9f0xBXeng-NuTRJoGIyQ3KISoIVT1CON2NLFOC-HQWpBIRZt4YrBS9fTKG3vjFJI68qFS8l8QFtG36Hht-Vp0coIZdqS1SM957z7cUP2HD3rqjy9xzxP6Z5f-TNqczg3dXNi7Pi_-AJX0zQW</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ANALOGIFREMGANGSM TE VED FREMSTILLING AV TERAPEUTISK VIRKSOMME 7-SUBSTITUERTE THEOFYLLINDERIVATER</title><source>esp@cenet</source><creator>KISS, PAL ; VIRAG, SANDOR ; HEJA, GERGELY ; SEBESTYEN, GYULA ; KOVACS, GABOR ; GOENCZI, CSABA ; MINKER, EMIL ; SZUETS, TAMAS ; SZOMOR, MARIA ; PALOSI, ENDRE ; SZVOBODA, IDA ; KUN, JUDIT ; KORBONITS, DEZSO</creator><creatorcontrib>KISS, PAL ; VIRAG, SANDOR ; HEJA, GERGELY ; SEBESTYEN, GYULA ; KOVACS, GABOR ; GOENCZI, CSABA ; MINKER, EMIL ; SZUETS, TAMAS ; SZOMOR, MARIA ; PALOSI, ENDRE ; SZVOBODA, IDA ; KUN, JUDIT ; KORBONITS, DEZSO</creatorcontrib><description>Antitussive compounds of the formula I (I) or physiologically acceptable acid addition salts thereof are disclosed, where A stands for straight or branched chain C1-5 alkylene or R1 stands for straight or branched chain C1-10 alkyl, halogenoalkyl, hydroxyalkyl, C5-6 cycloalkyl, vinyl, 2-ethoxyethyl, carbonylalkyl or aminoalkyl of the formula wherein R stands for hydrogen or methyl, n is 0 to 3, R2 stands for hydrogen or straight or branched chain alkyl, R3 stands for hydrogen or straight or branched chain alkyl or, R2 and R3 together with the nitrogen atom may form a 5-6 membered ring, which ring can optionally contain an oxygen or a second nitrogen atom, the latter, optionally substituted by methyl or, R1 can stand for a phenyl group of the formula R4R5C6H3 wherein R4 and R5 represent independently hydrogen, chlorine, hydroxy, methoxy, ethoxy, methyl or amino or, R1 may further stand for hydroxy, in this case the compound of the formula I may exist according to the conditions in the form of tautomers of the formula Ia (Ia) or (Ib) and R1 may further stand for benzyl, 2,2-diphenylethyl or theophyllin-7-yl-methyl.</description><edition>4</edition><language>nor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1989</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890208&DB=EPODOC&CC=NO&NR=159794C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19890208&DB=EPODOC&CC=NO&NR=159794C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KISS, PAL</creatorcontrib><creatorcontrib>VIRAG, SANDOR</creatorcontrib><creatorcontrib>HEJA, GERGELY</creatorcontrib><creatorcontrib>SEBESTYEN, GYULA</creatorcontrib><creatorcontrib>KOVACS, GABOR</creatorcontrib><creatorcontrib>GOENCZI, CSABA</creatorcontrib><creatorcontrib>MINKER, EMIL</creatorcontrib><creatorcontrib>SZUETS, TAMAS</creatorcontrib><creatorcontrib>SZOMOR, MARIA</creatorcontrib><creatorcontrib>PALOSI, ENDRE</creatorcontrib><creatorcontrib>SZVOBODA, IDA</creatorcontrib><creatorcontrib>KUN, JUDIT</creatorcontrib><creatorcontrib>KORBONITS, DEZSO</creatorcontrib><title>ANALOGIFREMGANGSM TE VED FREMSTILLING AV TERAPEUTISK VIRKSOMME 7-SUBSTITUERTE THEOFYLLINDERIVATER</title><description>Antitussive compounds of the formula I (I) or physiologically acceptable acid addition salts thereof are disclosed, where A stands for straight or branched chain C1-5 alkylene or R1 stands for straight or branched chain C1-10 alkyl, halogenoalkyl, hydroxyalkyl, C5-6 cycloalkyl, vinyl, 2-ethoxyethyl, carbonylalkyl or aminoalkyl of the formula wherein R stands for hydrogen or methyl, n is 0 to 3, R2 stands for hydrogen or straight or branched chain alkyl, R3 stands for hydrogen or straight or branched chain alkyl or, R2 and R3 together with the nitrogen atom may form a 5-6 membered ring, which ring can optionally contain an oxygen or a second nitrogen atom, the latter, optionally substituted by methyl or, R1 can stand for a phenyl group of the formula R4R5C6H3 wherein R4 and R5 represent independently hydrogen, chlorine, hydroxy, methoxy, ethoxy, methyl or amino or, R1 may further stand for hydroxy, in this case the compound of the formula I may exist according to the conditions in the form of tautomers of the formula Ia (Ia) or (Ib) and R1 may further stand for benzyl, 2,2-diphenylethyl or theophyllin-7-yl-methyl.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1989</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFi70KwjAYALM4iPoM5gU6iErp-Jl-SUObRPIHTiVInEQL9f0xBXeng-NuTRJoGIyQ3KISoIVT1CON2NLFOC-HQWpBIRZt4YrBS9fTKG3vjFJI68qFS8l8QFtG36Hht-Vp0coIZdqS1SM957z7cUP2HD3rqjy9xzxP6Z5f-TNqczg3dXNi7Pi_-AJX0zQW</recordid><startdate>19890208</startdate><enddate>19890208</enddate><creator>KISS, PAL</creator><creator>VIRAG, SANDOR</creator><creator>HEJA, GERGELY</creator><creator>SEBESTYEN, GYULA</creator><creator>KOVACS, GABOR</creator><creator>GOENCZI, CSABA</creator><creator>MINKER, EMIL</creator><creator>SZUETS, TAMAS</creator><creator>SZOMOR, MARIA</creator><creator>PALOSI, ENDRE</creator><creator>SZVOBODA, IDA</creator><creator>KUN, JUDIT</creator><creator>KORBONITS, DEZSO</creator><scope>EVB</scope></search><sort><creationdate>19890208</creationdate><title>ANALOGIFREMGANGSM TE VED FREMSTILLING AV TERAPEUTISK VIRKSOMME 7-SUBSTITUERTE THEOFYLLINDERIVATER</title><author>KISS, PAL ; VIRAG, SANDOR ; HEJA, GERGELY ; SEBESTYEN, GYULA ; KOVACS, GABOR ; GOENCZI, CSABA ; MINKER, EMIL ; SZUETS, TAMAS ; SZOMOR, MARIA ; PALOSI, ENDRE ; SZVOBODA, IDA ; KUN, JUDIT ; KORBONITS, DEZSO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NO159794CC3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>nor</language><creationdate>1989</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KISS, PAL</creatorcontrib><creatorcontrib>VIRAG, SANDOR</creatorcontrib><creatorcontrib>HEJA, GERGELY</creatorcontrib><creatorcontrib>SEBESTYEN, GYULA</creatorcontrib><creatorcontrib>KOVACS, GABOR</creatorcontrib><creatorcontrib>GOENCZI, CSABA</creatorcontrib><creatorcontrib>MINKER, EMIL</creatorcontrib><creatorcontrib>SZUETS, TAMAS</creatorcontrib><creatorcontrib>SZOMOR, MARIA</creatorcontrib><creatorcontrib>PALOSI, ENDRE</creatorcontrib><creatorcontrib>SZVOBODA, IDA</creatorcontrib><creatorcontrib>KUN, JUDIT</creatorcontrib><creatorcontrib>KORBONITS, DEZSO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KISS, PAL</au><au>VIRAG, SANDOR</au><au>HEJA, GERGELY</au><au>SEBESTYEN, GYULA</au><au>KOVACS, GABOR</au><au>GOENCZI, CSABA</au><au>MINKER, EMIL</au><au>SZUETS, TAMAS</au><au>SZOMOR, MARIA</au><au>PALOSI, ENDRE</au><au>SZVOBODA, IDA</au><au>KUN, JUDIT</au><au>KORBONITS, DEZSO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANALOGIFREMGANGSM TE VED FREMSTILLING AV TERAPEUTISK VIRKSOMME 7-SUBSTITUERTE THEOFYLLINDERIVATER</title><date>1989-02-08</date><risdate>1989</risdate><abstract>Antitussive compounds of the formula I (I) or physiologically acceptable acid addition salts thereof are disclosed, where A stands for straight or branched chain C1-5 alkylene or R1 stands for straight or branched chain C1-10 alkyl, halogenoalkyl, hydroxyalkyl, C5-6 cycloalkyl, vinyl, 2-ethoxyethyl, carbonylalkyl or aminoalkyl of the formula wherein R stands for hydrogen or methyl, n is 0 to 3, R2 stands for hydrogen or straight or branched chain alkyl, R3 stands for hydrogen or straight or branched chain alkyl or, R2 and R3 together with the nitrogen atom may form a 5-6 membered ring, which ring can optionally contain an oxygen or a second nitrogen atom, the latter, optionally substituted by methyl or, R1 can stand for a phenyl group of the formula R4R5C6H3 wherein R4 and R5 represent independently hydrogen, chlorine, hydroxy, methoxy, ethoxy, methyl or amino or, R1 may further stand for hydroxy, in this case the compound of the formula I may exist according to the conditions in the form of tautomers of the formula Ia (Ia) or (Ib) and R1 may further stand for benzyl, 2,2-diphenylethyl or theophyllin-7-yl-methyl.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ANALOGIFREMGANGSM TE VED FREMSTILLING AV TERAPEUTISK VIRKSOMME 7-SUBSTITUERTE THEOFYLLINDERIVATER |
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