ANALOGIFREMGANGSMAATE FOR FREMSTILLING AV ET FARMAKOLOGISK AKSEPTABELT POLYMERT MIDDEL SOM KAN FRIGI EN TERAPEUTISK VIRKENDE FORBINDELSE

ANALOGIFREMGANGSMAATE FOR FREMSTILLING AV ET FARMAKOLOGISK AKSEPTABELT POLYMERT MIDDEL SOM KAN FRIGI EN TERAPEUTISK VIRKENDE FORBINDELSE

The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable...

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Hauptverfasser: PITZELE, BARNETT SYLVAIN, JONES, PETER HADLEY
Format: Patent
Sprache:nor
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ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator PITZELE, BARNETT SYLVAIN
JONES, PETER HADLEY
description The present invention relates to novel compounds for the prophylaxis and treatment of Inflammatory Bowel disease (IBD) via the administration of an effective amount in a suitable pharmaceutical dosage of a polymeric agent for releasing 5,5'-azobis-salicylic acid which comprises a non-degradable anionic exchange resin and the dianionic form of 5,5'-azobis-salicylic acid. The 5,5'-azobis-salicylic acid undergoes bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANALOGIFREMGANGSMAATE FOR FREMSTILLING AV ET FARMAKOLOGISK AKSEPTABELT POLYMERT MIDDEL SOM KAN FRIGI EN TERAPEUTISK VIRKENDE FORBINDELSE
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