6,7-DIAL KOXY-4(4-SUBSTITUTED-PIPERIDINO)-QUINAZOLINES
6,7-Dialkoxy-4-[4-(substituted)piperidino]quinazolines wherein the 4-substituent is -(CHR1)m-Z wherein R1 is hydrogen or lower alkyl; m is 1 or 2, with the proviso that when m is 2, each R1 can be the same or different; Z is -N(R2)COR3, -OCONR4R5, N(R2)SO2R3 or -N(R2)CONR4R5 wherein R2 is hydrogen o...
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creator | JOHN KENDRICK STUBBS JOHN CHRISTOPHER DANILE WKZ SIMON FRASER CAMPBELL ALLAN LESLIE HAM |
description | 6,7-Dialkoxy-4-[4-(substituted)piperidino]quinazolines wherein the 4-substituent is -(CHR1)m-Z wherein R1 is hydrogen or lower alkyl; m is 1 or 2, with the proviso that when m is 2, each R1 can be the same or different; Z is -N(R2)COR3, -OCONR4R5, N(R2)SO2R3 or -N(R2)CONR4R5 wherein R2 is hydrogen or lower alkyl; R3 is lower alkyl, benzyl or phenyl; and each of R4 and R5 is hydrogen or is selected from group R3; and methods for their preparation. The compounds are phosphodiesterase inhibitors and cardiac stimulants. |
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The compounds are phosphodiesterase inhibitors and cardiac stimulants.</description><edition>4</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1985</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19851231&DB=EPODOC&CC=MY&NR=8500284A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19851231&DB=EPODOC&CC=MY&NR=8500284A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JOHN KENDRICK STUBBS</creatorcontrib><creatorcontrib>JOHN CHRISTOPHER DANILE WKZ</creatorcontrib><creatorcontrib>SIMON FRASER CAMPBELL</creatorcontrib><creatorcontrib>ALLAN LESLIE HAM</creatorcontrib><title>6,7-DIAL KOXY-4(4-SUBSTITUTED-PIPERIDINO)-QUINAZOLINES</title><description>6,7-Dialkoxy-4-[4-(substituted)piperidino]quinazolines wherein the 4-substituent is -(CHR1)m-Z wherein R1 is hydrogen or lower alkyl; m is 1 or 2, with the proviso that when m is 2, each R1 can be the same or different; Z is -N(R2)COR3, -OCONR4R5, N(R2)SO2R3 or -N(R2)CONR4R5 wherein R2 is hydrogen or lower alkyl; R3 is lower alkyl, benzyl or phenyl; and each of R4 and R5 is hydrogen or is selected from group R3; and methods for their preparation. The compounds are phosphodiesterase inhibitors and cardiac stimulants.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1985</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAz0zHXdfF09FHw9o-I1DXRMNENDnUKDvEMCQ1xddEN8AxwDfJ08fTz19QNDPX0c4zy9_H0cw3mYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxvpEWpgYGRhYmjsaEVQAAYisnJg</recordid><startdate>19851231</startdate><enddate>19851231</enddate><creator>JOHN KENDRICK STUBBS</creator><creator>JOHN CHRISTOPHER DANILE WKZ</creator><creator>SIMON FRASER CAMPBELL</creator><creator>ALLAN LESLIE HAM</creator><scope>EVB</scope></search><sort><creationdate>19851231</creationdate><title>6,7-DIAL KOXY-4(4-SUBSTITUTED-PIPERIDINO)-QUINAZOLINES</title><author>JOHN KENDRICK STUBBS ; JOHN CHRISTOPHER DANILE WKZ ; SIMON FRASER CAMPBELL ; ALLAN LESLIE HAM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MY8500284A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1985</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>JOHN KENDRICK STUBBS</creatorcontrib><creatorcontrib>JOHN CHRISTOPHER DANILE WKZ</creatorcontrib><creatorcontrib>SIMON FRASER CAMPBELL</creatorcontrib><creatorcontrib>ALLAN LESLIE HAM</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JOHN KENDRICK STUBBS</au><au>JOHN CHRISTOPHER DANILE WKZ</au><au>SIMON FRASER CAMPBELL</au><au>ALLAN LESLIE HAM</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>6,7-DIAL KOXY-4(4-SUBSTITUTED-PIPERIDINO)-QUINAZOLINES</title><date>1985-12-31</date><risdate>1985</risdate><abstract>6,7-Dialkoxy-4-[4-(substituted)piperidino]quinazolines wherein the 4-substituent is -(CHR1)m-Z wherein R1 is hydrogen or lower alkyl; m is 1 or 2, with the proviso that when m is 2, each R1 can be the same or different; Z is -N(R2)COR3, -OCONR4R5, N(R2)SO2R3 or -N(R2)CONR4R5 wherein R2 is hydrogen or lower alkyl; R3 is lower alkyl, benzyl or phenyl; and each of R4 and R5 is hydrogen or is selected from group R3; and methods for their preparation. The compounds are phosphodiesterase inhibitors and cardiac stimulants.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | 6,7-DIAL KOXY-4(4-SUBSTITUTED-PIPERIDINO)-QUINAZOLINES |
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