PRODUCTION OF LONG ACTING INSULIN PREPARATIONS
A stable insulin preparation having a lasting action and having low antigenicity is prepared by reaction of acidic groups of the insulin with basic groups of organic compounds. The reaction is carried out in an aqueous buffer solution which contains a protein-dissociating or protein-depolymerising a...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | BRUNO ANDRE HANSEN FINN HEDE ANDRESEN |
| description | A stable insulin preparation having a lasting action and having low antigenicity is prepared by reaction of acidic groups of the insulin with basic groups of organic compounds. The reaction is carried out in an aqueous buffer solution which contains a protein-dissociating or protein-depolymerising agent. Basic polypeptides, e.g. protamines, or cleavage products of basic polypeptides are preferred as organic compounds containing a basic group. The protein-dissociating or protein-depolymerising agent is preferably urea. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_MY7900169A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MY7900169A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_MY7900169A3</originalsourceid><addsrcrecordid>eNrjZNALCPJ3CXUO8fT3U_B3U_Dx93NXcARygZSnX3Coj6efQkCQa4BjkCNISTAPA2taYk5xKi-U5maQd3MNcfbQTS3Ij08tLkhMTs1LLYn3jTS3NDAwNLN0NCasAgBtQSVX</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PRODUCTION OF LONG ACTING INSULIN PREPARATIONS</title><source>esp@cenet</source><creator>BRUNO ANDRE HANSEN ; FINN HEDE ANDRESEN</creator><creatorcontrib>BRUNO ANDRE HANSEN ; FINN HEDE ANDRESEN</creatorcontrib><description>A stable insulin preparation having a lasting action and having low antigenicity is prepared by reaction of acidic groups of the insulin with basic groups of organic compounds. The reaction is carried out in an aqueous buffer solution which contains a protein-dissociating or protein-depolymerising agent. Basic polypeptides, e.g. protamines, or cleavage products of basic polypeptides are preferred as organic compounds containing a basic group. The protein-dissociating or protein-depolymerising agent is preferably urea.</description><edition>4</edition><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1979</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19791231&DB=EPODOC&CC=MY&NR=7900169A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19791231&DB=EPODOC&CC=MY&NR=7900169A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BRUNO ANDRE HANSEN</creatorcontrib><creatorcontrib>FINN HEDE ANDRESEN</creatorcontrib><title>PRODUCTION OF LONG ACTING INSULIN PREPARATIONS</title><description>A stable insulin preparation having a lasting action and having low antigenicity is prepared by reaction of acidic groups of the insulin with basic groups of organic compounds. The reaction is carried out in an aqueous buffer solution which contains a protein-dissociating or protein-depolymerising agent. Basic polypeptides, e.g. protamines, or cleavage products of basic polypeptides are preferred as organic compounds containing a basic group. The protein-dissociating or protein-depolymerising agent is preferably urea.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1979</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNALCPJ3CXUO8fT3U_B3U_Dx93NXcARygZSnX3Coj6efQkCQa4BjkCNISTAPA2taYk5xKi-U5maQd3MNcfbQTS3Ij08tLkhMTs1LLYn3jTS3NDAwNLN0NCasAgBtQSVX</recordid><startdate>19791231</startdate><enddate>19791231</enddate><creator>BRUNO ANDRE HANSEN</creator><creator>FINN HEDE ANDRESEN</creator><scope>EVB</scope></search><sort><creationdate>19791231</creationdate><title>PRODUCTION OF LONG ACTING INSULIN PREPARATIONS</title><author>BRUNO ANDRE HANSEN ; FINN HEDE ANDRESEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MY7900169A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1979</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BRUNO ANDRE HANSEN</creatorcontrib><creatorcontrib>FINN HEDE ANDRESEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BRUNO ANDRE HANSEN</au><au>FINN HEDE ANDRESEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PRODUCTION OF LONG ACTING INSULIN PREPARATIONS</title><date>1979-12-31</date><risdate>1979</risdate><abstract>A stable insulin preparation having a lasting action and having low antigenicity is prepared by reaction of acidic groups of the insulin with basic groups of organic compounds. The reaction is carried out in an aqueous buffer solution which contains a protein-dissociating or protein-depolymerising agent. Basic polypeptides, e.g. protamines, or cleavage products of basic polypeptides are preferred as organic compounds containing a basic group. The protein-dissociating or protein-depolymerising agent is preferably urea.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_MY7900169A |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PRODUCTION OF LONG ACTING INSULIN PREPARATIONS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T02%3A52%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BRUNO%20ANDRE%20HANSEN&rft.date=1979-12-31&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EMY7900169A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |