COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY

The invention relates to a novel class of compounds that exhibit activity inhibitory activity toward arginase, and pharmaceutical compositions comprising the compounds of the invention. Also provided herein are methods of treating cancer with the arginase inhibitors of the invention.

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Hauptverfasser: SJOGREN, Eric, B, VAN ZANDT, Michael, WHITEHOUSE, Darren, LI, Jim
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creator SJOGREN, Eric, B
VAN ZANDT, Michael
WHITEHOUSE, Darren
LI, Jim
description The invention relates to a novel class of compounds that exhibit activity inhibitory activity toward arginase, and pharmaceutical compositions comprising the compounds of the invention. Also provided herein are methods of treating cancer with the arginase inhibitors of the invention.
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY
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