METHODS AND COMPOSITIONS FOR TREATING HUNTER SYNDROME

METHODS AND COMPOSITIONS FOR TREATING HUNTER SYNDROME

The present invention provides, among other things, compositions and methods for CNS delivery of ldursulfase-beta, a human recombinant iduronate-2-sulfatase protein, for effective treatment of Hunter Syndrome. The compositions and methods provided by the present invention effectively reduce symptoms...

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Hauptverfasser: JIN, THONG-GYU, LEE, BYOUNG-JU, BYUN, HAN-YEUL, OKUYAMA, TORAYUKI, SEO, JIN-WOOK, LEE, KYUHYUN, KIM, YONGUL, JANG, IN-YOUNG
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator JIN, THONG-GYU
LEE, BYOUNG-JU
BYUN, HAN-YEUL
OKUYAMA, TORAYUKI
SEO, JIN-WOOK
LEE, KYUHYUN
KIM, YONGUL
JANG, IN-YOUNG
description The present invention provides, among other things, compositions and methods for CNS delivery of ldursulfase-beta, a human recombinant iduronate-2-sulfatase protein, for effective treatment of Hunter Syndrome. The compositions and methods provided by the present invention effectively reduce symptoms not only in brain and spinal cord but also in peripheral tissues including heart, liver, spleen, lung, and kidney.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title METHODS AND COMPOSITIONS FOR TREATING HUNTER SYNDROME
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