ANTIBODIES AGAINST OX40 AND USES THEREOF

Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light ch...

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Hauptverfasser:	JURE-KUNKEL, Maria, LEMAR, Hadia, HATCHER, Sandra V, QUIGLEY, Michael, SELBY, Mark J, KOZHICH, Alexander, T, WONG, Susan, Chien-Szu, STEVENS, Brenda, L, LEI, Ming, SRINIVASAN, Mohan, KORMAN, Alan, J, GOKEMEIJER, Jochem, GUIRNALDA, Patrick, RODRIGUEZ, Maria, YANG, Zheng, HUANG, Christine, HENNING, Karla A, FENG, Yan, AANUR, Praveen, CAI, Zhehong, HAN, Michelle Minhua, SCHWEIZER, Liang, MAURER, Mark F, CHAKRABORTY, Indrani, RAJPAL, Arvind, GARCIA, Marie-Michelle, Navarro, KEMPE, Thomas, D, THUDIUM, Kent, CHANG, Han, LONBERG, Nils, WANG, Xi-Tao, BARNHART, Bryan C, YAMNIUK, Aaron P, MILBURN, Christina, Maria, SHAO, Xiang
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.