PHARMACEUTICAL COMPOSITION CONTAINING A TETRAHYDROFOLIC ACID

PHARMACEUTICAL COMPOSITION CONTAINING A TETRAHYDROFOLIC ACID

The present invention relates to solid pharmaceutical compositions, in particular to oral contraceptives, comprising a progestogen, such as drospirenone; an estrogen, such as ethinylestradiol; a tetrahydrofolic acid or a pharmaceutically acceptable salt thereof, such as calcium 5-metyl-(6S)-tetrahyd...

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1. Verfasser: KRISTINA KING
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creator KRISTINA KING
description The present invention relates to solid pharmaceutical compositions, in particular to oral contraceptives, comprising a progestogen, such as drospirenone; an estrogen, such as ethinylestradiol; a tetrahydrofolic acid or a pharmaceutically acceptable salt thereof, such as calcium 5-metyl-(6S)-tetrahydrofolate; and at least one pharmaceutical acceptable excipient or carrier. The compositions of the invention provide good stability of the tetrahydrofolic acid upon storage while still ensuring a fast and reliable release of the estrogen and the progestogen present in the composition.
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title PHARMACEUTICAL COMPOSITION CONTAINING A TETRAHYDROFOLIC ACID
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