1-PYRAZOLYL-3- (4- ( (2 -ANILINOPYRIMIDIN- 4 - YL) OXY) NAPTHTHALEN- 1 - YL) UREAS AS P38 MAP KINASE INHIBITORS
There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, suc...
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| creator | ONIONS, STUART, THOMAS KING-UNDERWOOD, JOHN BROECKX, RUDY, LAURENT, MARIA ITO, KAZUHIRO FILLIERS, WALTER, FERDINAND LONGSHAW, ALISTAIR, IAN COPMANS, ALEX, HERMAN CHARRON, CATHERINE, ELISABETH |
| description | There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and COPD. |
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KING-UNDERWOOD, JOHN ; BROECKX, RUDY, LAURENT, MARIA ; ITO, KAZUHIRO ; FILLIERS, WALTER, FERDINAND ; LONGSHAW, ALISTAIR, IAN ; COPMANS, ALEX, HERMAN ; CHARRON, CATHERINE, ELISABETH</creatorcontrib><description>There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and COPD.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180926&DB=EPODOC&CC=MY&NR=167798A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180926&DB=EPODOC&CC=MY&NR=167798A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ONIONS, STUART, THOMAS</creatorcontrib><creatorcontrib>KING-UNDERWOOD, JOHN</creatorcontrib><creatorcontrib>BROECKX, RUDY, LAURENT, MARIA</creatorcontrib><creatorcontrib>ITO, KAZUHIRO</creatorcontrib><creatorcontrib>FILLIERS, WALTER, FERDINAND</creatorcontrib><creatorcontrib>LONGSHAW, ALISTAIR, IAN</creatorcontrib><creatorcontrib>COPMANS, ALEX, HERMAN</creatorcontrib><creatorcontrib>CHARRON, CATHERINE, ELISABETH</creatorcontrib><title>1-PYRAZOLYL-3- (4- ( (2 -ANILINOPYRIMIDIN- 4 - YL) OXY) NAPTHTHALEN- 1 - YL) UREAS AS P38 MAP KINASE INHIBITORS</title><description>There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and COPD.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyjELwjAUBOAuDqL-BXljO2SoLbaOT43kYZqENIJxKUXiJLZQ_z9m6C7cccN3y2TImfEWH1p6yQoGaRkL6Q4YKpKkdFRq6EyKQQkMvMxA330GCo0TTqDkUfJZbpZjCzGmqKFBA1dS2HIgJehITtt2nSxe_XsKm3lXyfbC3UmwMA5dmMb-GT7h2zU-31fVocbi7-EHyWgz1g</recordid><startdate>20180926</startdate><enddate>20180926</enddate><creator>ONIONS, STUART, THOMAS</creator><creator>KING-UNDERWOOD, JOHN</creator><creator>BROECKX, RUDY, LAURENT, MARIA</creator><creator>ITO, KAZUHIRO</creator><creator>FILLIERS, WALTER, FERDINAND</creator><creator>LONGSHAW, ALISTAIR, IAN</creator><creator>COPMANS, ALEX, HERMAN</creator><creator>CHARRON, CATHERINE, ELISABETH</creator><scope>EVB</scope></search><sort><creationdate>20180926</creationdate><title>1-PYRAZOLYL-3- (4- ( (2 -ANILINOPYRIMIDIN- 4 - YL) OXY) NAPTHTHALEN- 1 - YL) UREAS AS P38 MAP KINASE INHIBITORS</title><author>ONIONS, STUART, THOMAS ; 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | 1-PYRAZOLYL-3- (4- ( (2 -ANILINOPYRIMIDIN- 4 - YL) OXY) NAPTHTHALEN- 1 - YL) UREAS AS P38 MAP KINASE INHIBITORS |
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