POLYMORPHIC FORMS OF 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYLBENZOFURAN-5-YL) PIPERAZINE HYDROCHLORIDE

THE INVENTION RELATES TO NEW CRYSTALLINE MODIFICATIONS OF THE HYDROCHLORIDE OF 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYL-BENZOFURAN-5-YL)-PIPERIZINE, CRYSTALLINE MODIFICATION OF THE DIHYDROCHLORIDE OF 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYL-BENZOFURAN-5-YL)-PIPERIZINE AND AMORPHOUS 1-[4-(5...

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Hauptverfasser: HELFERT, BERND, KNIEL, HEIKE, BOTTCHER, HENNING, BATHE, ANDREAS, BARTELS, MATTHIAS, RUDOLPH, SUSANNE, NEUENFELD, STEFFEN
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creator HELFERT, BERND
KNIEL, HEIKE
BOTTCHER, HENNING
BATHE, ANDREAS
BARTELS, MATTHIAS
RUDOLPH, SUSANNE
NEUENFELD, STEFFEN
description THE INVENTION RELATES TO NEW CRYSTALLINE MODIFICATIONS OF THE HYDROCHLORIDE OF 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYL-BENZOFURAN-5-YL)-PIPERIZINE, CRYSTALLINE MODIFICATION OF THE DIHYDROCHLORIDE OF 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYL-BENZOFURAN-5-YL)-PIPERIZINE AND AMORPHOUS 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYL-BENZOFURAN-5-YL)-PIPERIZINE HYDROCHLORIDE WHICH ARE SUITABLE IN PARTICULAR FOR THE PREPARATION OF SOLID MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF DEPRESSIVE DISORDERS, ANXIETY DISORDERS, BIPOLAR DISORDERS, MANIA, DEMENTIA, SUBSTANCE-RELATED DISORDERS, SEXUAL DYSFUNCTIONS, EATING DISORDERS, OBESITY, FIBROMYALGIA, SLEEPING DISORDERS, PSYCHIATRIC DISORDERS, CEREBRAL INFARCT, TENSION, FOR THE THERAPY OF SIDE-EFFECTS IN THE TREATMENT OF HYPERTENSION, CEREBRAL DISORDERS, CHRONIC PAIN, ACROMEGALY, HYPOGONADISM, SECONDARY AMENORRHEA, PREMENSTRUAL SYNDROME AND UNDESIRED PUERPERAL LACTATION.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title POLYMORPHIC FORMS OF 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYLBENZOFURAN-5-YL) PIPERAZINE HYDROCHLORIDE
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