SPIRO-TETRACYCLIC RING COMPOUNDS AS BETASECRETASE MODULATORS AND METHODS OF USE

THE PRESENT INVENTION COMPRISES A NEW CLASS OF COMPOUNDS USEFUL FOR THE MODULATION OF BETA-SECRETASE ENZYME ACTIVITY AND FOR THE TREATMENT OF BETA-SECRETASE MEDIATED DISEASES, INCLUDING ALZHEIMER?S DISEASE (AD) AND RELATED CONDITIONS. IN ONE EMBODIMENT, THE COMPOUNDS HAVE A GENERAL FORMULA (I); WHER...

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Hauptverfasser: WHITE, RYAN, CHENG, ALAN C, PATEL, VINOD F, GORE, VIJAY KESHAV, LIU, QINGYIAN, HUANG, HONGBING, MARX, ISAAC, YUAN, CHESTER C, QIAN, WENYUAN, BRYAN, MARIAN C, LA, DANIEL, MA, VU VAN, CHEN, JIAN J, KREIMAN, CHARLES, HUA, ZIHAO, HUMAN, JASON B, WEISS, MATTHEW, EPSTEIN, OLEG, AMEGADZIE, ALBERT, DINEEN, THOMAS
Format: Patent
Sprache:eng
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