IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS

THE PRESENT INVENTION RELATES TO COMPOUNDS OF THE FORMULA 1 WHEREIN R¹, R ², R³, R⁴, R⁶, R⁷ AND A ARE AS DEFINED. COMPOUNDS OF THE FORMULA 1 HAVE ACTIVITY INHIBITING PRODUCTION OF A -PEPTIDE. THE INVENTION ALSO RELATES TO PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING DISEASES AND DISORDERS, F...

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Hauptverfasser: MICHAEL AARON BRODNEY, KAREN JEAN COFFMAN
Format: Patent
Sprache:eng
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Zusammenfassung:THE PRESENT INVENTION RELATES TO COMPOUNDS OF THE FORMULA 1 WHEREIN R¹, R ², R³, R⁴, R⁶, R⁷ AND A ARE AS DEFINED. COMPOUNDS OF THE FORMULA 1 HAVE ACTIVITY INHIBITING PRODUCTION OF A -PEPTIDE. THE INVENTION ALSO RELATES TO PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING DISEASES AND DISORDERS, FOR EXAMPLE, NEURODEGENERATIVE AND/OR NEUROLOGICAL DISORDERS, E.G., ALZHEIMER'S DISEASE, IN A MAMMAL COMPRISING COMPOUNDS OF THE FORMULA 1.