HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING

Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an a...

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Hauptverfasser: AMY VENTURINI, MICHAEL PASKIND, ANGELA WIDOM, JOHN G. ELVIN, JOCHEN G. SALFELD, SARA CARMEN, BORIS LABKOVSKY, GEERTRUIDA M. VELDMAN, THOR LAS HOLTET, SUBHASHIS BANERJEE, STEPHEN SMITH, MICHAEL WHITE, NICHOLAS W. WARNE, ELAINE J. DERBYSHIRE, ZEHRA KAYMAKCALAN, STUART FRIEDRICH, MICHAEL ROGUSKA, ALEXANDER R. DUNCAN, PAUL SAKORAFAS, ANGELA MYLES, SARAH L. DU FOU, DANIEL E. TRACEY
Format: Patent
Sprache:eng
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