METHODS FOR IDENTIFYING COMPOUNDS FOR REGULATING MUSCLE MASS OR FUNCTION USING CORTICOTROPIN RELEASING FACTOR RECEPTORS
SCREENING METHODS FOR IDENTIFYING COMPOUNDS THAT BIND TO OR ACTIVATE CORTICOTROPIN RELEASING FACTOR2 RECEPTORS (CRF2R) AND REGULATE OR POTENTIALLY REGULATE SKELETAL MUSCLE MASS OR FUNCTION IN VIVO. ALSO DISCLOSED ARE SCREENING METHODS FOR IDENTIFYING COMPOUNDS THAT PROLONG OR AUGMENT THE ACTIVATION...
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| creator | SHELDON, RUSSELL JAMES ISFORT, ROBERT JOSEPH |
| description | SCREENING METHODS FOR IDENTIFYING COMPOUNDS THAT BIND TO OR ACTIVATE CORTICOTROPIN RELEASING FACTOR2 RECEPTORS (CRF2R) AND REGULATE OR POTENTIALLY REGULATE SKELETAL MUSCLE MASS OR FUNCTION IN VIVO. ALSO DISCLOSED ARE SCREENING METHODS FOR IDENTIFYING COMPOUNDS THAT PROLONG OR AUGMENT THE ACTIVATION OF CRF2RS OR OF CRF2R SIGNAL TRANSDUCTION PATHWAYS, INCREASE CRF2R OR INCREASE CRF EXPRESSION ARE PROVIDED. PHARMACEUTICAL COMPOSITION COMPOSITIONS COMPRISING CRF2R AGONISTS, ANTIBODIES TO CRF2R AND METHODS FOR INCREASING SKELETAL MUSCLE MASS OR FUNCTION OR FOR THE TREATMENT OF SKELETAL MUSCLE ATROPHY USING CRF2R AS THE TARGET FOR INTERVENTION AND METHODS FOR TREATMENT OF MUSCULAR DYSTROPHIES ARE DISCRIBED. |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE |
| title | METHODS FOR IDENTIFYING COMPOUNDS FOR REGULATING MUSCLE MASS OR FUNCTION USING CORTICOTROPIN RELEASING FACTOR RECEPTORS |
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