PHARMACEUTICAL COMPOUNDS

A PHARMACEUTICAL COMPOUND OF THE FORMULA:@@FORMULA 1@@IN WHICH N IS 0, 1 OR 2 AND R1 IS ATTACHED AT ANY OF THE POSITIONS 5, 6, 7, 8, 9, OR 10, AND EACH R1 IS HALO, TRIFLUOROMETHYL, C1-4 ALKOXY, HYDROXY, NITRO, C1-4 ALKYL, C1-4 ALKYLTHIO, HYDROXY-C1-4 ALKYL, HYDROXY-C1-4 ALKYL, HYDROXY-C1-4ALKOXY, TR...

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Hauptverfasser: COLIN PETER DELL, COLIN WILLIAM SMITH
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COLIN WILLIAM SMITH
description A PHARMACEUTICAL COMPOUND OF THE FORMULA:@@FORMULA 1@@IN WHICH N IS 0, 1 OR 2 AND R1 IS ATTACHED AT ANY OF THE POSITIONS 5, 6, 7, 8, 9, OR 10, AND EACH R1 IS HALO, TRIFLUOROMETHYL, C1-4 ALKOXY, HYDROXY, NITRO, C1-4 ALKYL, C1-4 ALKYLTHIO, HYDROXY-C1-4 ALKYL, HYDROXY-C1-4 ALKYL, HYDROXY-C1-4ALKOXY, TROFLUOROMETHOXY, CARBOXY, -COOR5 WHERE R5 IS AN ESTER GROUP, -CONR6R7 OR -NR6R7 WHERE R6 AND R7 ARE EACH HYDROGEN OR C1-4 ALKYL;@@R2 IS PHENYL, NAPHTHYL OR HETEROARYL SELECTED FROM THIENYL, PYRIDYL, BENZOTHEINYL, QUINOLINYL, BENZOFURANYL OR BENZIMIDAZOLYL, SAID PHENYL, NAPHTYL AND HETEROARYL GROUPS BEING OPTIONALLY SUBSTITUTED, OR R2 IS FURANYL OPTIONALLY SUBSTITUTED WITH C1-4; ALKYL;@@R3 IS NITRILE, CARBOXY, -COOR8 WHERE R8 IS AN ESTER GROUP, -CONR9R10 WHERE R9 AND R10 ARE EACH HYDROGEN OR C1-4ALKYL, OR R11SO2- WHERE R11 IS C1-4 ALKYL OR OPTIONALLY SUBSTITUTED PHENYL; AND@@R4 IS -NR12R13, -NHCOR12, -N(COR12)2 OR -N=CHOCH2R12 WHERE R12 AND R13 ARE EACH HYDROGEN OR C1-4 ALKYL OPTIONALLY SUBSTITUTED WITH CARBOXY,@@WHERE X IS C2-4 ALKYLENE, OR -NHSO2R14 WHERE R14 IS C1-4 ALKYL OR OPTIONALLY SUBSTITUTED PHENYL; PROVIDED THAT WHEN N IS 0, R4 IS NITRILE AND R4 IS -NH2, R2 IS NOT PHENYL OR PHENYL SUBSTITUTED IN THE PARA-POSITION WITH A SINGLE CHLORO, HYDROXY OR METHOXY SUBSTITUENT;@AND SALT THEREOF.@
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COLIN WILLIAM SMITH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MY111368A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1999</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>COLIN PETER DELL</creatorcontrib><creatorcontrib>COLIN WILLIAM SMITH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>COLIN PETER DELL</au><au>COLIN WILLIAM SMITH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PHARMACEUTICAL COMPOUNDS</title><date>1999-12-31</date><risdate>1999</risdate><abstract>A PHARMACEUTICAL COMPOUND OF THE FORMULA:@@FORMULA 1@@IN WHICH N IS 0, 1 OR 2 AND R1 IS ATTACHED AT ANY OF THE POSITIONS 5, 6, 7, 8, 9, OR 10, AND EACH R1 IS HALO, TRIFLUOROMETHYL, C1-4 ALKOXY, HYDROXY, NITRO, C1-4 ALKYL, C1-4 ALKYLTHIO, HYDROXY-C1-4 ALKYL, HYDROXY-C1-4 ALKYL, HYDROXY-C1-4ALKOXY, TROFLUOROMETHOXY, CARBOXY, -COOR5 WHERE R5 IS AN ESTER GROUP, -CONR6R7 OR -NR6R7 WHERE R6 AND R7 ARE EACH HYDROGEN OR C1-4 ALKYL;@@R2 IS PHENYL, NAPHTHYL OR HETEROARYL SELECTED FROM THIENYL, PYRIDYL, BENZOTHEINYL, QUINOLINYL, BENZOFURANYL OR BENZIMIDAZOLYL, SAID PHENYL, NAPHTYL AND HETEROARYL GROUPS BEING OPTIONALLY SUBSTITUTED, OR R2 IS FURANYL OPTIONALLY SUBSTITUTED WITH C1-4; ALKYL;@@R3 IS NITRILE, CARBOXY, -COOR8 WHERE R8 IS AN ESTER GROUP, -CONR9R10 WHERE R9 AND R10 ARE EACH HYDROGEN OR C1-4ALKYL, OR R11SO2- WHERE R11 IS C1-4 ALKYL OR OPTIONALLY SUBSTITUTED PHENYL; AND@@R4 IS -NR12R13, -NHCOR12, -N(COR12)2 OR -N=CHOCH2R12 WHERE R12 AND R13 ARE EACH HYDROGEN OR C1-4 ALKYL OPTIONALLY SUBSTITUTED WITH CARBOXY,@@WHERE X IS C2-4 ALKYLENE, OR -NHSO2R14 WHERE R14 IS C1-4 ALKYL OR OPTIONALLY SUBSTITUTED PHENYL; PROVIDED THAT WHEN N IS 0, R4 IS NITRILE AND R4 IS -NH2, R2 IS NOT PHENYL OR PHENYL SUBSTITUTED IN THE PARA-POSITION WITH A SINGLE CHLORO, HYDROXY OR METHOXY SUBSTITUENT;@AND SALT THEREOF.@</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PHARMACEUTICAL COMPOUNDS
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