ANTIBODIES AGAINST WEST NILE VIRUS AND THERAPEUTIC AND PROPHYLACTIC USES THEREOF

The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particular...

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Hauptverfasser: THEODORE OLIPHANT, CHRISTOPHER MICHAEL DOANE, MICHAEL DIAMOND
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creator THEODORE OLIPHANT
CHRISTOPHER MICHAEL DOANE
MICHAEL DIAMOND
description The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV), infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating symptoms associated with WNV infection, said methods comprising administering to a human subject an effective amount of one or more antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions. La presente invencion se refiere a las composiciones que comprenden anticuerpos o fragmentos de los mismos que se enlazan inmunoespecificamente a uno o mas antigenos de un flavivirus, particularmente del virus del Nilo Occidental (WNV), y los metodos para prevenir, tratar o mejorar los sintomas asociados con una infeccion por flavivirus, particularmente del virus del Nilo Occidental (WNV) utilizando dichas composiciones. En particular, la presente invencion se refiere a los metodos para prevenir, tratar o mejorar los sintomas asociados con la infeccion por el WNV, los metodos comprenden administrarle a un sujeto humano una cantidad efectiva de uno o mas anticuerpos o fragmentos de los mismos que se enlazan inmunoespecificamente a un antigeno de WNV. La presente invencion tambien se refiere a las composiciones detectables o de diagnostico que comprenden los anticuerpos o fragmentos de los mismos que se enlazan inmunoespecificamente a un antigeno de WNV y los metodos para detectar o diagnosticar la infeccion por WNV, utilizando dichas composiciones.
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language eng ; spa
recordid cdi_epo_espacenet_MXPA06014795A
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title ANTIBODIES AGAINST WEST NILE VIRUS AND THERAPEUTIC AND PROPHYLACTIC USES THEREOF
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