HIGHLY PURE BASES OF 3,3-DIPHENYL PROPYLAMINE MONOESTERS
The invention relates to a compound of general formula (I) wherein A represents deuterium or hydrogen, R represents a group selected from C1-6 alkyl, C3-10 cycloalkyl or phenyl, which can be substituted by C1-3 alkoxy, fluorine, chlorine, bromine, iodine, nitro, amino, hydroxyl, oxo, mercapto or deu...
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| creator | ROLAND DREWS |
| description | The invention relates to a compound of general formula (I) wherein A represents deuterium or hydrogen, R represents a group selected from C1-6 alkyl, C3-10 cycloalkyl or phenyl, which can be substituted by C1-3 alkoxy, fluorine, chlorine, bromine, iodine, nitro, amino, hydroxyl, oxo, mercapto or deuterium. The C atom marked with a * (star) can be present in an (R) configuration, in an (S)-configuration or a mixture thereof. The invention is characterised in that the above-mentioned compounds are free bases with a degree of purity of more than 97 wt %. The invention also relates to a method for the production of highly pure compounds of general formula (I) and to the use thereof in the production of medicaments.
La presente invencion se refiere a un compuesto de la formula general (I): ver formula (I), en la que A representa deuterio o hidrogeno; R representa un grupo seleccionado de alquilo de 1 a 6 atomos de carbono, cicloalquilo de 3 a 10 atomos de carbono o fenilo; que pueden estar sustituidos con alcoxi de 1 a 3 atomos de carbono, fluor, cloro, bromo, yodo, nitro, amino, hidroxilo, oxo, mercapto o deuterio. El atomo de carbono marcado con asterisco (*) puede estar presente en una configuracion (R), en una configuracion (S) o como una mezcla de ellas. La invencion se caracteriza porque los compuestos mencionados arriba son bases libres con un grado de pureza de mas de 97 por ciento en peso. La invencion se refiere tambien a un metodo para producir compuestos de alta pureza de la formula general (I), y a su uso en la produccion de medicamentos. |
| format | Patent |
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La presente invencion se refiere a un compuesto de la formula general (I): ver formula (I), en la que A representa deuterio o hidrogeno; R representa un grupo seleccionado de alquilo de 1 a 6 atomos de carbono, cicloalquilo de 3 a 10 atomos de carbono o fenilo; que pueden estar sustituidos con alcoxi de 1 a 3 atomos de carbono, fluor, cloro, bromo, yodo, nitro, amino, hidroxilo, oxo, mercapto o deuterio. El atomo de carbono marcado con asterisco (*) puede estar presente en una configuracion (R), en una configuracion (S) o como una mezcla de ellas. La invencion se caracteriza porque los compuestos mencionados arriba son bases libres con un grado de pureza de mas de 97 por ciento en peso. La invencion se refiere tambien a un metodo para producir compuestos de alta pureza de la formula general (I), y a su uso en la produccion de medicamentos.</description><edition>7</edition><language>eng ; spa</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050603&DB=EPODOC&CC=MX&NR=PA05003562A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050603&DB=EPODOC&CC=MX&NR=PA05003562A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ROLAND DREWS</creatorcontrib><title>HIGHLY PURE BASES OF 3,3-DIPHENYL PROPYLAMINE MONOESTERS</title><description>The invention relates to a compound of general formula (I) wherein A represents deuterium or hydrogen, R represents a group selected from C1-6 alkyl, C3-10 cycloalkyl or phenyl, which can be substituted by C1-3 alkoxy, fluorine, chlorine, bromine, iodine, nitro, amino, hydroxyl, oxo, mercapto or deuterium. The C atom marked with a * (star) can be present in an (R) configuration, in an (S)-configuration or a mixture thereof. The invention is characterised in that the above-mentioned compounds are free bases with a degree of purity of more than 97 wt %. The invention also relates to a method for the production of highly pure compounds of general formula (I) and to the use thereof in the production of medicaments.
La presente invencion se refiere a un compuesto de la formula general (I): ver formula (I), en la que A representa deuterio o hidrogeno; R representa un grupo seleccionado de alquilo de 1 a 6 atomos de carbono, cicloalquilo de 3 a 10 atomos de carbono o fenilo; que pueden estar sustituidos con alcoxi de 1 a 3 atomos de carbono, fluor, cloro, bromo, yodo, nitro, amino, hidroxilo, oxo, mercapto o deuterio. El atomo de carbono marcado con asterisco (*) puede estar presente en una configuracion (R), en una configuracion (S) o como una mezcla de ellas. La invencion se caracteriza porque los compuestos mencionados arriba son bases libres con un grado de pureza de mas de 97 por ciento en peso. La invencion se refiere tambien a un metodo para producir compuestos de alta pureza de la formula general (I), y a su uso en la produccion de medicamentos.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDw8HT38IlUCAgNclVwcgx2DVbwd1Mw1jHWdfEM8HD1i_RRCAjyD4j0cfT19HNV8PX383cNDnENCuZhYE1LzClO5YXS3AxKbq4hzh66qQX58anFBYnJqXmpJfG-EQGOBqYGBsamZkaOxkQpAgCqQik0</recordid><startdate>20050603</startdate><enddate>20050603</enddate><creator>ROLAND DREWS</creator><scope>EVB</scope></search><sort><creationdate>20050603</creationdate><title>HIGHLY PURE BASES OF 3,3-DIPHENYL PROPYLAMINE MONOESTERS</title><author>ROLAND DREWS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MXPA05003562A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2005</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ROLAND DREWS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ROLAND DREWS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HIGHLY PURE BASES OF 3,3-DIPHENYL PROPYLAMINE MONOESTERS</title><date>2005-06-03</date><risdate>2005</risdate><abstract>The invention relates to a compound of general formula (I) wherein A represents deuterium or hydrogen, R represents a group selected from C1-6 alkyl, C3-10 cycloalkyl or phenyl, which can be substituted by C1-3 alkoxy, fluorine, chlorine, bromine, iodine, nitro, amino, hydroxyl, oxo, mercapto or deuterium. The C atom marked with a * (star) can be present in an (R) configuration, in an (S)-configuration or a mixture thereof. The invention is characterised in that the above-mentioned compounds are free bases with a degree of purity of more than 97 wt %. The invention also relates to a method for the production of highly pure compounds of general formula (I) and to the use thereof in the production of medicaments.
La presente invencion se refiere a un compuesto de la formula general (I): ver formula (I), en la que A representa deuterio o hidrogeno; R representa un grupo seleccionado de alquilo de 1 a 6 atomos de carbono, cicloalquilo de 3 a 10 atomos de carbono o fenilo; que pueden estar sustituidos con alcoxi de 1 a 3 atomos de carbono, fluor, cloro, bromo, yodo, nitro, amino, hidroxilo, oxo, mercapto o deuterio. El atomo de carbono marcado con asterisco (*) puede estar presente en una configuracion (R), en una configuracion (S) o como una mezcla de ellas. La invencion se caracteriza porque los compuestos mencionados arriba son bases libres con un grado de pureza de mas de 97 por ciento en peso. La invencion se refiere tambien a un metodo para producir compuestos de alta pureza de la formula general (I), y a su uso en la produccion de medicamentos.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HIGHLY PURE BASES OF 3,3-DIPHENYL PROPYLAMINE MONOESTERS |
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